Product Details
Sustanon 250 10ml 250mg Sterile multi dose vial
$50.00
Sustanon 250 is a popular testosterone blend (mixture) and is without question the most popular and well known blend ever made. Manufactured by Organon, the idea behind Sustanon 250 was to provide the best of small (short) and large (long) ester testosterones in a single compound. This would allow the individual to maintain stable blood levels of the testosterone hormone with an infrequent injection schedule while simultaneously receiving fast acting benefits.
The limited injection frequency makes Sustanon 250 a perfect compound for the treatment of low testosterone. It allows the individual to maintain stable levels without the need for constantly pinning themselves with a needle, but this is truly the only advantage of this testosterone. Sustanon 250 will not provide any advantage over a single ester testosterone compound to a performance athlete. In a performance capacity we will find the individual will still be required to inject the hormone frequently if he is to maintain not only stable blood levels but peaked blood levels. Many often inaccurately assume Sustanon 250 is superior over single ester testosterone forms due to the fact that it carries four distinct testosterones in a single injection. As for the basic functioning traits of testosterone, they will be the same with Sustanon 250 as they are with all testosterone forms. They will be no more or less powerful or effective.
Sustanon 250 Functions & Traits:
Sustanon 250 is a testosterone hormone. Although synthetic it is a perfect replica of the naturally produced primary male androgen testosterone. By the esters that are attached, this is what defines Sustanon 250 and differentiates it from other testosterone compounds. The compound carries a mixture of small and large esters in a precise dose. It is the precise dose of each of the four testosterone esters that make it. You could take four other testosterones and combine them in the same dosing strength but this would not make it Sustanon 250. This is important because there are underground labs that try to pass off other mixtures as Sustanon 250. The precise makeup of Organon’s product is as follows:
- 30mg Testosterone Propionate
- 60mg Testosterone Phenylpropionate
- 60mg Testosterone Isocaproate
- 100mg Testosterone Decanoate
This total mixture gives us 250mg of testosterone per milliliter. Sustanon 250 will also be found in single dose ampules, not vials and each ampule will contain this 250mg concentration. One thing you may have noticed is that the composition of Sustanon 250 is very similar to Omnadren, a testosterone blend manufactured by Jelfa. The original Omnadren mixture was identical to Sustanon 250 with one exception. Omnadren originally carried 100mg of Testosterone Caproate instead of Testosterone Decanoate. However, modern Omnadren now carries the Decanoate ester making it identical to Sustanon 250.
As a testosterone hormone, Sustanon 250 is perfect for treating low testosterone. Testosterone is an essential hormone for men and women; however, men require approximately ten times that of women. The hormone is responsible for sexual development and maturation but it is also responsible for the upkeep, maintenance and function of several key areas of our lives. This is a hormone that plays a role on our physical, mental and sexual well-being, and when levels fall to low we can suffer in numerous ways in all of those areas. The symptoms and effects of low testosterone are not in any way what we’d call life threatening; however, they can tremendously suppress your overall quality of life. The condition is also extremely unhealthy and if left ignored can lead to or help promote conditions that are indeed life threatening. If you suffer from any of the following symptoms there’s a good chance you suffer from low testosterone and Sustanon 250 can easily remedy the problem:
- Loss of Libido (can refer to partial or total loss)
- Erectile Dysfunction (inability to maintain or obtain and erection)
- Loss of Muscle Mass (despite diet & exercise)
- Loss of Strength (despite diet & exercise)
- Increased Body Fat (despite diet & exercise)
- Loss of Mental Clarity
- Decreased Ability to Focus
- Lethargy
- Insomnia
- Irritability
- Decreased Energy
- Depression
- Weakened Immune System
By administering Sustanon 250 such symptoms will not only fade away they will fade away rapidly and bring about notable improvements in those areas of your life. Of course, this is assuming the symptoms are low testosterone related. More importantly, when we treat low testosterone we protect ourselves from the gateway issues that can arise when the problem is ignored.
Interestingly enough, while the use of exogenous testosterone may lead to moderate cholesterol issues, prolonged low testosterone has been linked to high cholesterol. If you suffer from low testosterone there really is no reason you should suffer when treatment is not only available but easily so with compounds like Sustanon 250.
Then we have performance enhancement, and it will be other functions and traits of the testosterone hormone that are of interest here. The performance athlete will notice improvements in every area of his life that the low testosterone patient benefited from. However, in this case he will be taking his testosterone levels to a much higher level. This high level will bring about enormous enhancements in five key areas that are associated with physical progress. And from these five traits, we will find we have a hormone that is one of the most versatile hormones at our disposal and perfect for nearly all male performance related goals. The specific traits of Sustanon 250 in this category include:
Enhanced Protein Synthesis: Protein synthesis refers to the rate by-which cells build proteins, the primary building block of muscle tissue. Protein synthesis is enhanced and in return so is this basic function in anabolism.
Enhanced Nitrogen Retention: All lean muscle tissue is comprised of approximately 16% nitrogen. When nitrogen levels fall this puts us at great risk in falling into a catabolic state. The more nitrogen we retain the greater our anabolic atmosphere will remain. As was with protein synthesis, this trait will prove very useful in bulking and cutting cycles as will all the basic high testosterone level promoted traits.
Increased Red Blood Cell Count: Red blood cells are responsible for carrying oxygen to and through the blood. As blood oxygenation levels increase this increases the ability of the muscle to perform. This trait will play an imperative role in endurance and recovery.
Increased IGF-1 Output: Insulin-Like Growth Factor-1 (IGF-1) is a highly potent and powerful naturally produced peptide hormone with tremendous anabolic power. While highly anabolic it also plays an extremely important role on our body’s recovery process. This is a hormone that affects nearly every cell in the human body and with more available there is more to do what IGF-1 does best.
Inhibition of Glucocorticoid Hormones: Glucocorticoid hormones or stress hormones are in many ways the very opposite of anabolic steroids. These hormones destroy muscle tissue and promote fat storage; cortisol is the most well-known glucocorticoid. By using a compound like Sustanon 250 and achieving high testosterone levels, we ensure glucocorticoids while necessary to a degree to our health do not become dominant in the body.
The basic functions and traits of Sustanon 250 are fairly straightforward. There’s nothing magical about this hormone, nothing out of the ordinary but it is still a remarkable product. The testosterone hormone, while very simple to understand is dramatically powerful, beneficial and perhaps the most important hormone of all.
Effects of Sustanon 250:
By now we should have a good understanding of the effects of Sustanon 250 simply by understanding its functions and traits. If you suffer from low testosterone and supplement with Sustanon 250 you will suffer no more; problem solved. Then we have performance enhancement, and we want to break down the effects of Sustanon 250 in a way that gives them a real life understanding.
During an off-season bulking cycle this is one of the best times to use Sustanon 250. High testosterone levels create the perfect atmosphere for muscle growth. Granted, the calories have to be there. If you’re not eating enough all the testosterone in the world wont’ help you grow. However, the combination of a well-planned diet and high testosterone levels will see tremendous advancements in lean tissue growth. Of equal importance, high testosterone levels will enhance your metabolic rate. Those who have higher testosterone levels will gain less body fat during their off-season than those who do not have higher testosterone levels. Make no mistake, you can still gain a lot of unwanted body fat if you’re not careful with your off-season nutrition, but high testosterone levels will give you the ability to make better use of this period in training.
While many understand high testosterone levels are beneficial when growing, many fail to understand how beneficial they can be when cutting. A cutting cycle is a perfect time to supplement with Sustanon 250. Due to its tremendously powerful anabolic nature this hormone will protect lean muscle tissue better than just about anything else. When we diet we must burn more calories than we consume and this puts our lean muscle tissue at risk. The body will take what it needs to meet its energy demands from wherever it can get it, and this is often out muscle tissue. The idea is to force the body to burn fat, not muscle and a well-planned diet can help but it can only go so far. At some point the body will go into survival mode and protect the stored body fat and tap into muscle stores for its energy needs unless there is an anabolic protectant such as what high testosterone levels can provide.
Protecting lean tissue is the primary benefit of high testosterone levels when cutting, but it’s not the only one. The use of Sustanon 250 will enable the individual to burn body fat at a more efficient rate due to the metabolic enhancement high levels will provide. It is, however, important to note that many will need to use less Sustanon 250 during their cutting phase compared to off-season phase due to estrogen sensitivity. This will make more sense once we dive into the side effects section. However, some often make the mistake of taking their testosterone levels too low during the cutting phase. Remember, it took high testosterone levels to build the mass you have and it will take similarly high levels to maintain it. You can cut the total dosing down during the cutting phase but you need to be smart about it and consider the inclusion of other anabolic steroids.
The effects of Sustanon 250 do not end with what we’ve discussed so far. High testosterone levels will greatly enhance muscular endurance. You will not tire out as fast when your testosterone levels are high. The use of Sustanon 250 will also dramatically improve your overall rate of recovery and this is invaluable. Recovery is where progress is made. Progress isn’t actually made in the gym when we train. When we train we are actually tearing down muscle tissue. It is the repair process that brings about progress. High testosterone levels will see this progress enhanced and undertaken in a more efficient and thorough manner. This makes high testosterone levels very beneficial to athletes as recovery and endurance are key components to athletic performance. As a bonus, Sustanon 250 will increase the individual’s strength, again a key component to athletic success.
Side Effects of Sustanon 250:
For the healthy adult male, healthy excluding low testosterone, Sustanon 250 is an extremely well-tolerated anabolic steroid. There are possible side effects of Sustanon 250 use, but they are also largely controllable with proper use. We will find that certain side effects of Sustanon 250 are highly dependent on genetic predispositions, but overall safe supplementation is more than possible.
For the low testosterone patient, he will have the easiest time combating the side effects of Sustanon 250. In this case, while side effects are possible he is merely replacing the testosterone he’s lacking. Then we have the performance athlete and he will be taking his testosterone levels far above and beyond what could ever be naturally produced. Most men can tolerate high testosterone levels very well but there is generally a cutoff point. However, this cutoff point can vary greatly from one man to the next. Further, this individual will need to exercise more caution than the low testosterone patient and often take steps that a therapeutic setting may not require. In order to help you understand the possible side effects of Sustanon 250 we have broken them down into their separate categories along with all the information you’ll need.
[1] Estrogenic:
The side effects of Sustanon 250 will most commonly include those of an estrogenic nature. The testosterone hormone is highly susceptible to the aromatase enzyme, which is responsible for the conversion of testosterone to estrogen. As estrogen levels rise, this can lead to and promote three common side effects associated with anabolic steroid use. The primary estrogenic side effects of Sustanon 250 include gynecomastia and excess water retention. If excess water retention becomes severe this can have a profound negative effect on blood pressure. Severe water retention is the leading cause of high blood pressure with anabolic steroid use. It is also very controllable.
In order to combat the estrogenic side effects of Sustanon 250 an anti-estrogen medication is often recommended. You have two choices in anti-estrogen medications, Selective Estrogen Receptor Modulators (SERM’s) or Aromatase Inhibitors (AI’s). AI’s will be the most effective as they will directly inhibit the aromatase process and reduce total serum estrogen levels. SERM’s will not inhibit aromatization or lower estrogen levels, but they will bind to the receptors thereby preventing estrogenic action. SERM’s can be very useful in combating gynecomastia, but they are often not enough to prevent water retention in some men. Unfortunately, AI’s can also have a negative effect on cholesterol that appears to be greatly exasperated when combined with the use of exogenous testosterone. SERM’s will have no negative effect on cholesterol. In fact, they may promote healthy cholesterol levels due to their estrogen like activity in the liver. If you can get the job done with a SERM it should always be your first choice.
An important note on water retention, and this is very important regarding off-season use of Sustanon 250. An overabundance in calories, especially carbohydrates will promote water retention. Excess calories are needed for growth but often not near the levels most assume. A moderate increase above maintenance caloric consumption is often all that’s needed. However, many will eat so much that they will inevitably hold a lot of water and this water retention may become worse with the inclusion of exogenous testosterone. Control your caloric intake, especially your carbohydrate intake and you’ll have a much easier time controlling water retention.
[2] Androgenic:
Sustanon 250 is a highly androgenic hormone and can produce related effects. The androgenic side effects of Sustanon 250 include acne, accelerated hair loss in those predisposed to male pattern baldness and body hair growth. These side effects of Sustanon 250 are highly dependent on genetic predispositions. Sensitivity to androgenicity plays a role but is dependent on the testosterone hormone’s interaction with the 5-alpha reductase enzyme. This enzyme is responsible for reducing testosterone to dihydrotestosterone (DHT) and as DHT activity increases it can lead to the related effects. In order to combat the androgenic side effects of Sustanon 250 some may find the use of a 5-alpha reductase inhibitor such as Finasteride to be warranted. Not all men will need a related inhibitor but some will find it helps. However, it is important to note that a 5-alpha reductase inhibitor will not completely reduce the steroid’s androgenicity. Those who are extremely sensitive to androgenic effects may find this steroid is not for them or should at least be used in minimal amounts.
[3] Cardiovascular:
The use of testosterone can have a negative impact on cholesterol, particularly HDL cholesterol (good cholesterol). However, it does not appear to be very significant in most cases. Low HDL suppression is possible but it’s often inconsequential. However, when combined with the use of an AI it appears to be exasperated. According to the data at hand, the use of testosterone at a dosing of 250-600mg per week with an AI will promote an approximate 20% reduction in HDL cholesterol levels. The total reduction as you can see remains statistically the same in that dosing range. Once again, for this reason SERM’s should be your first choice in place of AI’s in order to combat estrogenic activity. But, SERM’s won’t always be enough and there is hope. If an AI is needed with your Sustanon 250 you should ensure you put in a lot of effort into controlling your cholesterol levels. This means a cholesterol friendly diet rich in omega fatty acids, low in saturated fats and low in simple sugars. It also means incorporating plenty of cardiovascular activity into your routine.
[4] Testosterone:
Regardless of who you are or why you’re using Sustanon 250 the inclusion of this anabolic steroid will suppress your natural testosterone production. For the low testosterone patient this is of no concern. Such an individual is not producing enough testosterone to begin with. For the performance athlete, while using Sustanon 250, again this is of no concern. Sustanon 250 will provide all the testosterone the body needs. However, the concern arises for this individual once his cycle and use comes to an end. When use comes to an end natural testosterone production will begin again. However, it will take a long time for your levels to return to normal. This can lead to a temporary low testosterone state and the associated symptoms. It can also lead to cortisol becoming the dominant hormone in your body making the progress made on cycle very difficult to impossible to maintain.
Due to the testosterone suppression caused by Sustanon 250, once use is discontinued most all men are encouraged to implement a Post Cycle Therapy (PCT) plan. A solid PCT plan will include SERM’s like Nolvadex (Tamoxifen Citrate) and Clomid (Clomiphene Citrate) and the peptide hormone HCG (Human Chorionic Gonadotropin). This will greatly speed up the recovery process. A PCT plan will not return you to normal on it’s own. There is no PCT plan on earth that can do this. However, a PCT plan will ensure you have enough testosterone for proper bodily function while your natural testosterone levels continue to rise.
Important notes on natural testosterone recovery. Natural recovery assumes no prior low testosterone condition existed. It also assumes severe damage was not done to the Hypothalamic-Pituitary-Testicular-Axis (HPTA).
[5] Hepatotoxicity:
Sustanon 250 is not hepatotoxic and will present no stress or damage to the liver.
Sustanon 250 Administration:
In a therapeutic setting to treat low testosterone, Sustanon 250 doses will normally fall in the 250mg every 3-4 week range with one injection every 3 weeks being most common. The total duration of treatment is indefinite. Low testosterone normally needs to be treated for life. We can remedy the problem but it will in most cases require continual treatment.
In a performance capacity, Sustanon 250 doses commonly range from 250-1,000mg per week. 250mg per week is enough to combat testosterone suppression caused by the use of other anabolic steroids. For a true anabolic effect, most will find 500mg per week to be effective. 500mg per week will be very tolerable for most men and often all the Sustanon 250 they’ll need. Many men will be able to tolerate 750-1,000mg per week. Higher testosterone levels should produce greater results; however, they will also increase the probability of negative side effects. How great this increase in probability is will be dependent on the individual and can greatly vary from one man to the next. Doses above 1,000mg per week will greatly exasperate potential negative side effects.
As for stacking, Sustanon 250 will stack well with all anabolic steroids. During off-season cycles, Deca Durabolin or any Nandrolone compound is often beneficial along with possible additions of Anadrol or Dianabol. During the cutting phase, steroids like Anavar, Masteron, Primobolan, Trenbolone and Winstrol will prove useful. You will also find the Trenbolone hormone to be very valuable during off-season use.
An important note; some will find Sustanon 250 painful to inject. Sustanon 250 contains the Propionate ester and a small segment of the population will find this ester irritates the injected area. This will prohibit some from using the steroid.
Availability of Sustanon 250:
Sustanon 250 is one of the most expensive testosterone compounds on the market. However, it is in high supply and is one of the easiest anabolic steroids to buy. Organon manufactures the compound in numerous countries. The most common include Karachi’s (Pakistan), Nile’s (Egypt), Redi-Jects (Mexico) and the original Sustanon 250 products from Brazil, Italy, England, Belgium, and Portugal.
There are numerous other labs and pharmaceutical companies that manufacture the Sustanon 250 mixture. One of the most common is Russian Infar and Induject-250 by Alpha Pharma. Countless underground labs also manufacture the mixture in generic form. However, there is always a risk of an inferior product when purchasing an underground label. As for the Organon brands, counterfeits are also a risk, especially when it’s from Brazil, Pakistan and Egypt. You will need to exercise caution and do some hard digging on your supplier before you make a purchase. Also familiarize yourself with the Organon labels thoroughly as the country of origin will determine exactly how the product is supposed to look.
An important note; Sustanon 250 is not legally available in the U.S. The U.S. FDA has never approved it and Organon has never sought out approval. There are many Organon products that have been U.S. FDA approved, but in recent years they have continually withdrawn more of their products from this market due to the strict legislation on anabolic steroids in the U.S.
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Anadrol (Oxymetholone)
Anadrol (commonly called by athletes “A50” or “A-bombs”) was initially developed as a compound to help people with anemia, and has since been used very successfully to aid people who are suffering from many other diseases where weight loss is a concern. Thus, it is clearly an effective agent for promoting weight gain, increasing appetite, gaining strength, and increasing Red Blood Cell count. And, as with most Anabolic/Androgenic Steroids (AAS), it has its downsides as well. Anadrol 50 will inhibit your body’s natural production of hormones (testosterone, etc ), will negatively affect your blood lipid profile, can cause water retention, is notorious for causing headaches, and is also highly liver toxic (in fact, it has the worst reputation for hepatoxicity out of all steroids). Paradoxically, although one the benefits touted by its original manufacturer (Syntex) is that it can be used to stimulate weight gain through increasing appetite, taking too much may actually inhibit your appetite!
Anadrol Effects on Body
I think, in order to gain a complete understanding of the Anadrol 50 effects on body, we need to take a look at its advantages contrasted with its disadvantages. Anadrol is a DHT-derived compound, and is 17-Alpha-Alkylated steroid, meaning that it has been altered at the 17th carbon position to survive oral ingestion. Most oral steroids are 17aa, and this helps them make it through your liver in a useful form. Sounds great, right? Lets 17alpha-alkylate everything! Well as you can imagine, there’s a down side.
Anadrol Side Effects
This 17aa alteration, which makes it possible for Anadrol to survive its first pass through your liver, also makes it very taxing on your liver. How taxing is Anadrol and how much weight can you gain from its use? Well, there was a 30 week study done on Anadrol and, as you can expect, a reasonable amount of side effects were noted. The fact that Anadrol causes some side effects has really never been in debate. But how effective was the drug? Well, first it should be mentioned that this study was done on people with AIDS related wasting, and they actually gained weight (8+kg) while the control group lost weight, and had increased mortality rates. (1). I suppose, if you’re in a study because you have a wasting disease which is also a terminal illness, you don’t want to end up in the control group. Anyway, weight gain in this study peaked at 19-20 weeks, though, so the last 10 weeks weren’t very productive in this respect. Clearly, you wouldn’t want to run Anadrol 50 for 20 weeks, given its toxicity, but after that, any effect in terms of weight and strength gains would be negligible. So, with regards to sides from Anadrol, and the sheer fact that this study lasted so long (30 weeks), it should be apparent that they can be kept under control and the drug can be used safely. People are commonly told to limit their intake of Anadrol to 4 weeks or less I’m a bit less conservative and think you can easily run Anadrol for 6 weeks or more.
From personal experience, however, I can tell you that gains from Anadrol are quite dramatic for the first 3 weeks and then quickly level off. Unfortunately, I find that the side effects experienced from Anadrol (which include a headache, bloating, elevated blood pressure, and a general “unwell” feeling for me) remain for the entire duration of use. But I find as usual, side effects for this drug are pretty much half legend and half truth. Since Anadrol 50 is derived from DHT, it cant actually convert to estrogen (via the aromatase enzyme), and its not a progestin or a compound with progestenic activity so the estrogenic (?) side effects produced by it are of a very mysterious nature. It has been speculated that perhaps it can stimulate the estrogen receptor without actually being converted to estrogen and that’s about as plausible an explanation as Ive heard. However, things really get strange, when Oxymetholone has been used in studies to alter the female reproductive/menstrual cycle; in those cases, it has lowered plasma progesterone levels! (7)One would expect that an AI (aromatase inhibitor) wouldn’t be of much use with this drug, but many have found that Letrozole (which has, in some cases been shown to reduce estrogen in the body to an undetectable amount)(6) can greatly reduce or even eliminate many of the more noticeable side effects of Anadrol, such as the bloating.
As I’ve stated, however, the sides from this drug are certainly no joke, but are easily preventable, and controllable. One study even showed very few sides for subjects using up to 100mgs of Oxymetholone (2). In the original UnderGround Steroid Hand Book, Dan Duchaine states that he used it at doses up to 150mgs/day. Clearly, Anadrol’s hepatoxicity has been a bit exaggerated, in some circles. Be that as it may, my suggestion is still to limit Anadrol’s use to 6 weeks, at a maximum even if just to err on the side of caution. Of course, I have personally run this drug for much longer..
How should we use Anadrol? Id probably be willing to include Anadrol in a cycle including injectable steroids, but not other 17aa compounds. Id make any 6-week-run of this compound begin at the start of a cycle, as a form of “jumpstart” towards seeing gains quickly. The quick gains you will get from Anadrol (up to a pound per day for the first 2 weeks are not uncommon in Steroid.com members) are also just as quick to disappear upon cessation of use .unless you are simply using it as a kickstarter, while waiting for your other compounds to kick-in. Ill go out on a limb here and say that utilizing Anadrol as a “Jumpstart” is the most popular use of this drug for athletes and bodybuilders today. Ill also say that this drug is immensely popular with strength athletes who dont have to worry about weight classes (Field athletes and strongmen), and with powerlifters in the heavier weight brackets. Its also important to note that in one study by Schroder et. Al (2) Anadrol showed that it has the ability to lower serum SHBG (Sex Hormone Binding Globulin which binds to your free test and makes it no longer useful for anabolism, among other things) concentrations by 54.9 25.8 and 45 16.2 nmol/l in the 50- and 100-mg treatment groups. This means there will be more free test circulating around your body when you take this drug and clearly, this would produce some synergy when stacked with other steroids. Given the large amounts of weight and strength which can be gained in a relatively short time span on this drug, I’m sure this comes as no surprise to many.
Another important and often understated characteristic of this compound is that Oxymetholone doesn’t bind well to the androgen receptor (Relative Binding Affinity = too low to be determined) (3) which is the lowest Ive ever read about. Basically, what this tells me is that there are a lot of non-receptor mediated effects from this steroid, making it a very potent addition to ANY BULKING stack, because it wont be competing for the receptor sites with the other steroids you’re using. Its also, as you may have guessed a very poor choice for a cutting stack.
Anadrol Cycles
What is an Anadrol Cycle? How much should you use? Well, this is actually one of the most interesting facts about Anadrol 50. You see, most steroids produce what we call a “dose respondent curve” which is a fancy way of saying “the more you use, the more you gain.”
Anadrol is one of the few steroids where the dose respondent curve flattens out very quickly. When you take 50mgs of Anadrol, you’ll make some very good gains. When you take 100mgs of Anadrol, you’ll make even more gains. However, it has been found that 100mgs/day is as effective for weight gain as 150mgs/day but produces less side effects and was less toxic (4). I feel that the jump from 50mgs to 100mgs constitutes an acceptable rise in benefit vs. cost, but this is not the case as dosages get over 100mgs. Now, lets see how 50mgs and 100mgs of Oxymetholone actually effect strength, when compared with each other:
Relative (%) changes in strength are shown for the groups receiving placebo (filled bars), 50 mg/day oxymetholone (open bars), and 100 mg/day oxymetholone (gray bars). Nos. above bars represent relative change (%) from baseline to week 12 for the 1-repetition maximum tests of strength. Error bars represent 1 SE from the mean. * Significant difference from placebo, P < 0.05; significant difference from placebo by Wilcoxon test, P < 0.02. See text for additional statistical analyses.
As you can see, in this study, doubling the dose of Anadrol 50 nearly doubled the strength gains of the test subjects. Now, when we look at changes in body composition from Oxymetholone (chart below) we can see that although the guys taking the 100mgs (vs. the 50mgs group) had more fat lost and more Lean Body Mass gained, it wasn’t as dramatic as the differences in strength gains between the two groups:
Changes in body composition are shown for the groups receiving placebo (filled bars), 50 mg of oxymetholone per day (open bars), and 100 mg per day (gray bars). Numbers above the bars represent the mean absolute changes and the error bars are 1 SE. For total lean body mass (LBM) and total fat, differences among the 3 groups were significant (P < 0.0001, one-way ANOVA). * Significant differences from placebo, P 0.001.
Although I am usually not inclined to posit speculations on why a particular drug does or doesn’t do something, in this case I will. Im guessing that the higher doses of Anadrol cause enough appetite suppression (at least anecdotally) to make eating rather difficult. It can also increase insulin resistance and glucose intolerance (5). This has the effect of making macronutrient absorption more inefficient, and could also be a factor in reducing gains when the dosage goes over 100mgs/day. Unfortunately, Anadrol also has a reasonably profound effect on your body’s natural hormonal system, on par with most other oral steroids, but not as bad as most injectables, and its certainly not as harsh on your lipid profile as many anabolics are
Anadrol Body Building
(2). As an interesting side note, some of the medical literature on this compound suggests a dose of 1-5mgs per kg of bodyweight. Ill pause a second here for you to figure out how absurdly high of a dose that would translate to for the average bodybuilder!
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Dianabol (Methandrostenolone)
Dianabol represents one of the most popular and one of the most important anabolic steroids of all time. Without question, this is the most popular oral steroid to ever hit the market and one of the most popular steroids in any form. While almost always found as an oral tablet, Dianabol can be found as an injectable solution, but the tablets represent the primary route of administration. Why is this steroid so important? In many ways it gave birth to the age of modern performance enhancement. It was not the first anabolic steroid used for that purpose, that would belong to testosterone, but Dianabol would open the door to a new wave of steroid use that has grown beyond what anyone expected.
Dianabol represents one of the only anabolic steroids that was developed for the sole purpose of performance enhancement. The compound did carry listed therapeutic uses at one time, but performance was the true reason this steroid was given life. Through the 1940’s and 50’s the Soviet Union had begun to dominate the Olympic games, and the use of testosterone by many of its athletes left the rest of the world lagging far behind. During this time, U.S. Olympic team Dr. John Ziegler would learn of the U.S.S.R.’s steroid use, and quickly would aid in ensuring his athletes would match up. In 1958, with the help of Dr. Ziegler, Ciba Pharmaceuticals would release the first batches of Methandrostenolone under the trade name Dianabol. The compound was designed in an effort to maintain the anabolic properties of testosterone with less androgenicity in a fast acting, powerful method. Seemingly overnight the steroid was a massive success, giving many U.S. athletes a distinct advantage over their Soviet rivals.
After its inception, Dianabol would quickly find its way into nearly every competitive sport imaginable. In conjunction with exogenous testosterone, this would birth an age of performance unlike the world had ever seen. The steroid would also rapidly become a staple in competitive bodybuilding where it has remained a favorite to this day. However, shortly after its release the U.S. FDA would begin to put a lot of pressure on Ciba in an effort to push the company to list true medical benefits of the steroid. The FDA would approve its use for the treatment osteoporosis in post-menopausal women as well as pituitary-deficient dwarfism, but the latter was withdrawn in the early 1980’s. Again the FDA would pressure Ciba for more information, but in 1983 under mounting pressure Ciba would discontinue the Dianabol tab. A few years later, the FDA would pull all Methandrostenolone brands from the shelf. Since that time Dianabol has not been legally manufactured in the United States, but is still manufactured heavily all over the world.
Dianabol Functions & Traits:
Methandrostenolone is a testosterone derived anabolic androgenic steroid. Officially, it is a structurally altered form of the primary male androgen testosterone. Dianabol is the testosterone hormone with an added double bond at the carbon one and two position. This slight alteration reduces the hormone’s androgenic nature. It also carries an added methyl group at the 17th carbon position that allows the hormone to survive oral ingestion, officially classifying Dianabol as a C17-alpha alkylated steroid. An important note, injectable Dianabol is also C17-alpha alkylated. The end result gives us an anabolic steroid with an androgenic rating of 40-60 with a much lower binding affinity to the androgen receptor compared to testosterone. However, it will also share a much weaker relationship for serum binding protein, which results in an extremely powerful anabolic steroid. If there’s any doubt, this is one extremely powerful anabolic steroid carrying a potent anabolic nature.
On a functional basis, Dianabol is one of the easier anabolic steroids to understand. This steroid will largely provide its anabolic benefits by enhancing protein synthesis, nitrogen retention and glycogenolysis. Protein synthesis represents the rate by which cells build proteins, the building blocks of muscle. Nitrogen retention, this is important as all muscle tissue is comprised of approximately 16% nitrogen. The more nitrogen we retain, the more anabolic we remain. Conversely, a nitrogen deficiency results in a catabolic or muscle wasting state. Then we’re left with glycogenolysis, which refers to the relationship and conversion between glycogen and glucose. Through enhanced glycogenolysis, we are able to make better use of our total carbohydrate consumption. While in many ways these traits are quite simple, they are strong enough to make Dianabol a remarkably powerful anabolic steroid.
Another important trait of Dianabol and perhaps one of the most important of all is the relationship it shares with other anabolic steroids. Dbol as it’s often called is not what we’d label as a base steroid. This is not an anabolic steroid we build a cycle around, but rather one we add to a well-planned stack. Dianabol has the ability to create unbelievable synergy when conjoined with other anabolic steroids. For example, you could supplement with 100mg of Trenbolone, Masteron or Equipoise per day (doses and steroids are simply being used as an example, not actual recommendations) and the results you’d receive from 50mg per day of Trenbolone, Masteron or Equipoise along side 50mg of Dianabol per day would be far more dramatic. You would have an identical amount of total milligrams of anabolic steroids with or without Dianabol, but the added Dianabol would provide greater enhancement.
Effects of Dianabol:
The effects of Dianabol can be summed up as fast acting and dramatic. In fact, it is more than possible for the individual to gain as much as 20lbs of mass in only a few weeks of Dianabol use. Total dosing will play a role, as will total caloric consumption, but a 20lb gain is very realistic. This makes Dianabol a premier off-season bulking steroid, and that will be its most common purpose of use. During this phase of use, the individual should also expect his strength to increase significantly. Dbol is actually one of the best strength increasing steroids on the market and along with mass can produce this result rapidly.
The effects of Dianabol are also greatly appreciated by many athletes; however, it is not as common as it once was in athletic enhancement circles. Due to the possible rapid increases in mass, many athletes will opt for steroids like Anavar or Winstrol, but it generally depends on the purpose of use. Due to the rapid and pronounced increases in strength, which can translate into more power and speed, this can be a solid athletic enhancer. The individual should also experience a level of enhanced recovery and endurance. When it comes to the weight gain, it’s important to remember that this will largely revolve around total caloric intake. While the steroid can promote enormous amounts of mass, you have to feed the body enough calories to reach this end. We wouldn’t call this the best athletic enhancing steroid due to other options, but if strength is the only true concern it could be a decent option.
Then we’re left with the cutting cycle, and you will not find Dianabol in such plans too often. Some competitive bodybuilders will use it early on in a cutting phase in order to maintain fullness, and it will provide lean tissue protection; however, there are better options. One problem with cutting cycle use can be the level of water retention this steroid can provide, which is normally the last thing you want when cutting. Such retention can be controlled, and the ability for this steroid to maintain strength can be appreciated, but there are better options.
Side Effects of Dianabol:
There are several possible side effects of Dianabol use. This is not the most dangerous anabolic steroid of all time, but it can carry a host of potential problems. A healthy adult male can manage the side effects of Dianabol, but you must understand them and how to combat them to pull this off. In order to achieve successful supplementation, we have broken down the possible side effects of Dianabol into their related categories along with all you need to know
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Dianabol 25mg 50 capsules Heat Sealed Tamper Proof Bottle
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Dianabol represents one of the most popular and one of the most important anabolic steroids of all time. Without question, this is the most popular oral steroid to ever hit the market and one of the most popular steroids in any form. While almost always found as an oral tablet, Dianabol can be found as an injectable solution, but the tablets represent the primary route of administration. Why is this steroid so important? In many ways it gave birth to the age of modern performance enhancement. It was not the first anabolic steroid used for that purpose, that would belong to testosterone, but Dianabol would open the door to a new wave of steroid use that has grown beyond what anyone expected.
Dianabol represents one of the only anabolic steroids that was developed for the sole purpose of performance enhancement. The compound did carry listed therapeutic uses at one time, but performance was the true reason this steroid was given life. Through the 1940’s and 50’s the Soviet Union had begun to dominate the Olympic games, and the use of testosterone by many of its athletes left the rest of the world lagging far behind. During this time, U.S. Olympic team Dr. John Ziegler would learn of the U.S.S.R.’s steroid use, and quickly would aid in ensuring his athletes would match up. In 1958, with the help of Dr. Ziegler, Ciba Pharmaceuticals would release the first batches of Methandrostenolone under the trade name Dianabol. The compound was designed in an effort to maintain the anabolic properties of testosterone with less androgenicity in a fast acting, powerful method. Seemingly overnight the steroid was a massive success, giving many U.S. athletes a distinct advantage over their Soviet rivals.
After its inception, Dianabol would quickly find its way into nearly every competitive sport imaginable. In conjunction with exogenous testosterone, this would birth an age of performance unlike the world had ever seen. The steroid would also rapidly become a staple in competitive bodybuilding where it has remained a favorite to this day. However, shortly after its release the U.S. FDA would begin to put a lot of pressure on Ciba in an effort to push the company to list true medical benefits of the steroid. The FDA would approve its use for the treatment osteoporosis in post-menopausal women as well as pituitary-deficient dwarfism, but the latter was withdrawn in the early 1980’s. Again the FDA would pressure Ciba for more information, but in 1983 under mounting pressure Ciba would discontinue the Dianabol tab. A few years later, the FDA would pull all Methandrostenolone brands from the shelf. Since that time Dianabol has not been legally manufactured in the United States, but is still manufactured heavily all over the world.
Dianabol Functions & Traits:
Methandrostenolone is a testosterone derived anabolic androgenic steroid. Officially, it is a structurally altered form of the primary male androgen testosterone. Dianabol is the testosterone hormone with an added double bond at the carbon one and two position. This slight alteration reduces the hormone’s androgenic nature. It also carries an added methyl group at the 17th carbon position that allows the hormone to survive oral ingestion, officially classifying Dianabol as a C17-alpha alkylated steroid. An important note, injectable Dianabol is also C17-alpha alkylated. The end result gives us an anabolic steroid with an androgenic rating of 40-60 with a much lower binding affinity to the androgen receptor compared to testosterone. However, it will also share a much weaker relationship for serum binding protein, which results in an extremely powerful anabolic steroid. If there’s any doubt, this is one extremely powerful anabolic steroid carrying a potent anabolic nature.
On a functional basis, Dianabol is one of the easier anabolic steroids to understand. This steroid will largely provide its anabolic benefits by enhancing protein synthesis, nitrogen retention and glycogenolysis. Protein synthesis represents the rate by which cells build proteins, the building blocks of muscle. Nitrogen retention, this is important as all muscle tissue is comprised of approximately 16% nitrogen. The more nitrogen we retain, the more anabolic we remain. Conversely, a nitrogen deficiency results in a catabolic or muscle wasting state. Then we’re left with glycogenolysis, which refers to the relationship and conversion between glycogen and glucose. Through enhanced glycogenolysis, we are able to make better use of our total carbohydrate consumption. While in many ways these traits are quite simple, they are strong enough to make Dianabol a remarkably powerful anabolic steroid.
Another important trait of Dianabol and perhaps one of the most important of all is the relationship it shares with other anabolic steroids. Dbol as it’s often called is not what we’d label as a base steroid. This is not an anabolic steroid we build a cycle around, but rather one we add to a well-planned stack. Dianabol has the ability to create unbelievable synergy when conjoined with other anabolic steroids. For example, you could supplement with 100mg of Trenbolone, Masteron or Equipoise per day (doses and steroids are simply being used as an example, not actual recommendations) and the results you’d receive from 50mg per day of Trenbolone, Masteron or Equipoise along side 50mg of Dianabol per day would be far more dramatic. You would have an identical amount of total milligrams of anabolic steroids with or without Dianabol, but the added Dianabol would provide greater enhancement.
Effects of Dianabol:
The effects of Dianabol can be summed up as fast acting and dramatic. In fact, it is more than possible for the individual to gain as much as 20lbs of mass in only a few weeks of Dianabol use. Total dosing will play a role, as will total caloric consumption, but a 20lb gain is very realistic. This makes Dianabol a premier off-season bulking steroid, and that will be its most common purpose of use. During this phase of use, the individual should also expect his strength to increase significantly. Dbol is actually one of the best strength increasing steroids on the market and along with mass can produce this result rapidly.
The effects of Dianabol are also greatly appreciated by many athletes; however, it is not as common as it once was in athletic enhancement circles. Due to the possible rapid increases in mass, many athletes will opt for steroids like Anavar or Winstrol, but it generally depends on the purpose of use. Due to the rapid and pronounced increases in strength, which can translate into more power and speed, this can be a solid athletic enhancer. The individual should also experience a level of enhanced recovery and endurance. When it comes to the weight gain, it’s important to remember that this will largely revolve around total caloric intake. While the steroid can promote enormous amounts of mass, you have to feed the body enough calories to reach this end. We wouldn’t call this the best athletic enhancing steroid due to other options, but if strength is the only true concern it could be a decent option.
Then we’re left with the cutting cycle, and you will not find Dianabol in such plans too often. Some competitive bodybuilders will use it early on in a cutting phase in order to maintain fullness, and it will provide lean tissue protection; however, there are better options. One problem with cutting cycle use can be the level of water retention this steroid can provide, which is normally the last thing you want when cutting. Such retention can be controlled, and the ability for this steroid to maintain strength can be appreciated, but there are better options.
Side Effects of Dianabol:
There are several possible side effects of Dianabol use. This is not the most dangerous anabolic steroid of all time, but it can carry a host of potential problems. A healthy adult male can manage the side effects of Dianabol, but you must understand them and how to combat them to pull this off. In order to achieve successful supplementation, we have broken down the possible side effects of Dianabol into their related categories along with all you need to know:
Estrogenic Qualities of Dianabol
Dianabol is a relatively strong estrogenic anabolic steroid due to the moderate level of aromatase activity it carries. While its aromatase activity is only moderate, this conversion actually leads Methandrostenolone to be converted to methylestradiol rather than estradiol, which is far more powerful than estradiol. This can make side effects like gynecomastia and water retention very possible with this steroid; in fact, they can appear seemingly overnight. Heavy water retention can also promote high blood pressure, which Dianabol is notorious for causing. Such effects can be controlled, and when it comes to high blood pressure this is something you’ll need to put some effort into ensuring does not become a problem.
In order to combat the estrogenic side effects of Dianabol, anti-estrogens are commonly recommended when supplementing with this steroid. You have two choices in anti-estrogens, Selective Estrogen Receptor Modulators (SERM’s) like Nolvadex (Tamoxifen Citrate) and Aromatase Inhibitors (AI’s) like Femara (Letrozole). SERM’s can be enough for some men and should be your first choice if they can get the job done. However, AI’s will be far more effective as they will directly inhibit aromatization and reduce serum estrogen levels. Unfortunately, AI’s can negatively affect cholesterol, as can Dianabol, and when conjoined this can prove potentially problematic. If an AI is used cholesterol management will be a priority, and it will be possible. However, SERM’s, while not always as effective will actually promote healthier cholesterol levels due to their estrogenic like activity in the liver.
Androgenic Qualities of Dianabol
Dianabol is not an extremely androgenic steroid, its androgenicity has been structurally reduced, but androgenic side effects are still possible. Such side effects of Dianabol use include acne, accelerated hair loss in those predisposed to male pattern baldness and body hair growth. Most men should not have a problem with such effects, response will be the final dictator, but most will remain clear. Although the odds are in your favor, such effects are brought on by Methandrostenolone being metabolized by the 5-alpha reductase enzyme. This is the same enzyme responsible for the reduction of testosterone to dihydrotestosterone, but the overall conversion here will result in very low amounts of dihydromethandrostenolone. This tells us 5-alpha reductase inhibitors like Finasteride that are often used to combat androgenic side effects will have very little if any affect on Dianabol.
Despite its reduced androgenicity, Dianabol can promote virilization symptoms in women. Such symptoms include body hair growth, a deepening of the vocal chords and clitoral enlargement. It is possible for some women to use this steroid without virilization symptoms with extremely low doses, but the odds are not favorable. Most all women should choose anabolic steroids with less translating androgenic activity to meet their needs.
Cardiovascular Effects of Dianabol
Dianabol can have a pronounced negative effect on cholesterol. This includes HDL cholesterol suppression and increases in LDL cholesterol, and the total changes can be significant. It is possible for total cholesterol levels to remain in a healthy range, but it is also possible for this healthy total reading to be misleading if HDL is suppressed heavily. Managing cholesterol during Dianabol use will be extremely important. Repeated use of this steroid as with many anabolic steroids could potentially lead to plaque buildup in the arteries overtime. It’s also extremely important to keep in mind the very possible additional strain on cholesterol brought on by the use of an AI when supplementing with Dianabol as total estrogen reductions will have a negative effect. Again, cholesterol maintenance will be extremely important.
As discussed, Dianabol can also play a negative role on blood pressure, which can be controlled by controlling water retention in most cases. When it comes to the blood pressure and cholesterol issues, the ultimate key to success will be your lifestyle. You should not supplement with this steroid if you already suffer from high blood pressure or cholesterol. If you are healthy enough for use, you should ensure your lifestyle is conducive to their maintenance. This should include a healthy diet that is rich in omega fatty acids, plenty of cardiovascular activity and an avoidance of any activity that promotes the opposite, negative end. Proper estrogen maintenance and control will also be important as estrogen plays an important role in cholesterol management. Yes, it is more than possible to supplement with Dianabol without high blood pressure and cholesterol, but you must put in the effort.
Testosterone Suppression with Dianabol
All anabolic steroids suppress natural testosterone production. While the total rate of suppression varies from one steroid to the next, with Dianabol it is very pronounced. For this reason, most men are encouraged to include some form of exogenous testosterone with their Dianabol use. Failure to include exogenous testosterone, regardless of your genetics or rumors you have heard will lead to a low testosterone condition. Such a condition comes with a host of possible symptoms and is extremely unhealthy. Even if symptoms do not show or are moderate at best, a low level condition will remain an unhealthy one. If you include exogenous testosterone, this problem is solved as the body will have all the testosterone it needs.
Once the use of Dianabol is complete and all the exogenous steroidal hormones have cleared your system, natural testosterone recovery will begin again. Natural recovery assumes no prior low testosterone condition. It also assumes no damage was done to the Hypothalamic-Pituitary-Testicular-Axis (HPTA) due to improper anabolic steroid use. While natural recovery will begin on its own, it will be slow. For this reason, most are encouraged to implement a Post Cycle Therapy (PCT) plan after anabolic steroid use. Such a plan will commonly include the SERM’s Nolvadex and Clomid, and often additional HCG. This will greatly speed up the recovery process, as well as its overall efficiency. It will not return your natural testosterone levels to normal on its own, if this is something you’ve been told it is a myth. However, it will ensure you have enough testosterone for proper bodily function while your levels continue to naturally rise. Total recovery will still take several months, but this will cut the total time down dramatically and ensure a smooth recovery.
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