Human Growth Hormone (HGH) is not only one of the most beneficial hormones our body produces, but one of the most sought after in exogenous form. In an exogenous form, HGH is identical to the naturally produced hormone, and represents not only one of the most beneficial exogenous hormones but one of the most well-tolerated among men and women. Its high level of toleration applies not only to medicinal use but performance enhancement as well.
Commonly, those in the media or in any popular culture conversation refer to Human Growth Hormone as an anabolic steroid. However, HGH is in no shape or form an anabolic steroid. Yes, it does carry strong anabolic properties, but being anabolic does not make something an anabolic steroid. Food is also highly anabolic, but no one would call chicken or ground beef an anabolic steroid.
The use of Human Growth Hormone was first successful in 1958. At this time, HGH was a pituitary extract; it was directly extracted from the pituitary of human cadavers. In 1985, the U.S. FDA would ban its use. Extracted HGH had been successful in many treatment plans, but it also proved to carry with it strong unsanitary disadvantages. In fact, pituitary HGH was linked to CJD, a degenerative brain disorder that is fatal. However, very few fell prey to CDJ, approximately 1% of all users, but this was enough for the FDA to impose a ban.
With the FDA banning HGH extract, soon after somatrem would be released. This was not a pure HGH match but rather a contaminant free variant of the hormone. Shortly after, Kabi Vitrum of Sweden would bring forth the means of synthesizing pure Human Growth Hormone. This would be a pure synthetic and contaminant form of HGH known as Somatropin. This process was made possible thanks to recombinant DNA technology, and since that time all synthetic HGH, regardless of the brand, is officially known as Somatropin. When it comes to the effectiveness and traits associated with Human Growth Hormone, synthetic or naturally derived there is no difference.
Human Growth Hormone is a protein hormone produced by the anterior pituitary gland. It is produced by all living human beings, and is at its highest levels during childhood. HGH represents one of the most important hormones in the human body as it affects our bones, skeletal muscle and internal organs, as well as plays roles in numerous other areas throughout the body.
Human Growth Hormone also supports the metabolism of carbohydrates, fats and minerals. Through its direct mode of action, it can also stimulate the growth of connective tissue. Beyond connective tissue growth, HGH has been shown to significantly increase the size and number of cells in skeletal muscle. The hormone will also further support triglyceride hydrolysis, which in turn will promote the reduction of adipose tissue or body fat. So effective in its abilities surrounding fat, HGH has been shown to significantly reduce total cholesterol levels. This, among many other things can be very useful to the anabolic steroid user as many steroids tend to support improper cholesterol levels.
In its direct functioning capacity, Human Growth Hormone sends a signal to the cells in the muscle, bone and adipose tissue to promote anabolism (muscle growth) and lipolysis (fat loss). However, it also carries indirect traits in that it increases gluconeogenesis and promotes insulin resistance. In the end, all these traits give us a reduced sensitivity to insulin, increased glucose levels and increases in the rate of lipolysis.
On a structural basis, it is important to note the exact or precise composition of HGH if you are going to purchase a synthetic form. This is important as there are many HGH variants or fragment hormones but they are not Somatropin. True Human Growth Hormone carries 191 amino acid residues making it identical to naturally produced HGH.
The effects of Human Growth Hormone are nothing short of tremendous. Through supplementation of Somatropin, we can see improvements in numerous areas of our physical wellbeing, and in some cases, they can be dramatic. In a therapeutic setting, HGH is most commonly used to treat pituitary dwarfism in children or to combat an HGH deficiency in adults. This could be caused by pituitary cancer or simply be due to a lacking of production that commonly occurs with age. HGH is also used to treat those with HIV or AIDS, and has proven extremely beneficial in numerous muscle wasting conditions. Synthetic HGH has also proven beneficial to burn victims, short bowel syndrome and Prader-Willi syndrome, but its most common purpose of use is as an anti-aging medication. When we look at the effects of HGH, it won’t be too hard to see how it can greatly improve the effects of aging.
In a performance setting, HGH has rapidly become one of the most sought after hormones on the market. It is tremendously anabolic; however, when used alone and at a moderate dose it is not well-known for promoting truly massive growth. For true performance related growth, the individual will normally need to use it in conjunction with anabolic steroids. Anabolic steroids and HGH appear to work in perfect harmony with one another. However, even when used alone Human Growth Hormone will promote recovery far greater than most any exogenous hormone, as well as carry a pronounced positive effect on the metabolism. As it pertains to healing, HGH carries tremendous healing properties that can be beneficial to nearly all areas of the human body.
Human Growth Hormone also shares a correlating role with the potent and powerful anabolic hormone Insulin-Like Growth Factor-1 (IGF-1). IGF-1 is highly anabolic, carries tremendous recovery properties and affects nearly every cell in the human body. The use of HGH will result in an increase in IGF-1; in fact, IGF-1 levels will remain elevated far past the elevated HGH levels. It is, however, important to keep in mind that IGF-1 can carry some antagonist effects to HGH, which could make the use of exogenous IGF-1 supplementation ill-advised during HGH use for some individuals.
Human Growth Hormone has in recent years been deemed the fountain of youth, and as we look at the effects of HGH it’s not too hard to see why. Will it prevent aging? Absolutely not, but it can undoubtedly make the aging process far more manageable. In short, there are very few healthy adults who would not benefit from HGH supplementation, and this includes not only in a performance setting but in all walks of life. To give you a direct understanding or appreciation, the effects of Human Growth Hormone can include the following in both men and women:
Overall, Human Growth Hormone is one of the safest hormones any man or woman can administer to their body. This is not a foreign substance, it is a hormone your body is well accustomed to, and more importantly, one it needs. While overall it is a tremendously safe hormone, there are possible side effects of Human Growth Hormone use. The most common side effects of HGH include water retention, specifically around the ankles and wrist, joint pain and headaches. Some may also experience flu like symptoms, but such symptoms normally only exist at the early stages of use and normally subside quickly.
The side effects of HGH can also include carpal tunnel syndrome, which in part is often due to water retention related effects. Such effects are most common among performance level doses of the hormone. Hypothyroidism, a deficiency in thyroid hormone production is also possible, especially with performance level doses. This issue can be remedied by the use of Cytomel (Liothyronine Sodium) or what is commonly referred to as T3. Some may also experience nausea, dizziness, respiratory infection and numbness of the skin. While possible, these side effects of Human Growth Hormone are the least likely with moderate edema, slight joint pain and headaches being the most common.
The side effects of Human Growth Hormone can become very problematic when the hormone is abused. Abuse will refer to extremely high doses; total use can be indefinite and often safe, but the dose must remain reasonable. HGH abuse can lead to enlarged hands, feet and jaw, and more severally to the enlargement of internal organs. The side effects of HGH can also include short-term type-2 diabetes due to the hormone’s ability to increase blood sugar and reduce insulin sensitivity.
The final possible side effect of Human Growth Hormone is an irritated injected area. Small lumps in the skin or an itchy feeling at the injected area are commonplace. You may need to move your injections around to find the most comfortable spot. However, many enjoy injecting their HGH into the same area every time as it is one of the few hormones that have been shown to have spot injection benefits. Injecting repeatedly into the same area has been shown to promote localized lipolysis, which will lead many men to always inject their HGH into the fatty tissue in their stomach.
Human Growth Hormone is an injectable hormone that can be administered subcutaneously or intramuscularly. When injected subcutaneously, HGH carries a bioavailability of approximately seventy-five percent. When injected intramuscularly, HGH carries a bioavailability of approximately sixty-three percent. The mode of administration will also affect the half-life of the Somatropin hormone. When injected subcutaneously, it will carry a half-life of approximately 3.8 hours. When injected intramuscularly, it will carry a half-life of approximately 4.9 hours. While this is a rather short half-life regardless of the mode of administration, keep in mind the total effects far outlast these numbers due to the pronounced and significant increases in IGF-1 production that stretch far past the twenty-four hour mark.
In a therapeutic setting, male Human Growth Hormone doses will normally fall in the 1-3iu per day range. Some may receive as much as 4iu’s per day, but this is rare. For the female patient, Human Growth Hormone doses will normally fall in the 1-2iu per day range. In some cases, the dose may be slightly less than 1iu per day, which can be common in long term anti-aging plans.
For the performance enhancing athlete, there can be a wide range of HGH doses. For male athletes, 2-4iu per day is most common, and can be extremely beneficial to athletes as well as those who are physique minded. Such a dose will promote fat loss and all the recovery and rejuvenation traits associated with the hormone. When coupled with anabolic steroids, due to the synergy created between HGH and anabolic steroids, you will see the standard steroid cycle greatly enhanced. The standard anabolic steroid cycle becomes far more beneficial. For the female HGH user, the same traits and benefits can be obtained with 1-2iu per day.
While the above doses will provide a tremendous benefit, in a performance setting in order to achieve truly remarkable muscle tissue growth the total dose will need to be increased. Most men will need 6-8iu’s per day and for a very long period of time. More can be used, and more will provide greater results, but it will also greatly exasperate the potential for negative side effects. Females who wish to approach true growth benefits will need to approach the 3-4iu per day range.
Regardless of the total dosing, Human Growth Hormone is not something that produces fast results. The hormone will be relatively useless if only used for a short period of time. In order to promote fat loss and enhance recovery, at minimum the individual will need 8-12 weeks of use with 16 weeks being far more effective. For true anabolic growth, the individual will need to plan on continuous HGH therapy at a decent dose for a minimum of six months. In a therapeutic setting, specifically anti-aging, total use will be indefinite. Most plans will call for continuous therapy or at least therapy that last the majority of the year.
Testosterone Cypionate
Testosterone is a hormone produced by all human beings and is the primary male sex hormone. Through our discussion, well take a look at Testosterone Cypionate, and examine the pros and cons of its use to improve performance in athletics and bodybuilding. Before we dive in, lets clear up a common misconception. Testosterone Cypionate is no more or less powerful or effective than its counterpart Testosterone Enanthate. The two compounds are virtually identical in every way.
Testosterone Cypionate is a synthetic version of the naturally produced testosterone hormone. This hormone is responsible for many different physical and mental characteristics in males. It promotes sex drive, fat loss, helps with gaining and maintaining lean muscle mass, increases bone density, and may even protect against heart disease. Whether it is naturally produced or through the use of Testosterone Cypionate, these traits do not change. All other steroids are actually the testosterone molecule that has been altered to change the properties of the hormone. Testosterone Cypionate carries a rating of 100 when measuring its anabolic/androgenic structure and this rating is used to measure all other steroids. This would make testosterone the “father” of all anabolic steroids used by athletes today. It should be noted; all testosterone compounds, including Testosterone Cypionate carry this anabolic/androgenic score of 100, as they are all merely testosterone.
Testosterone Cypionate is a highly anabolic and androgenic hormone making it a great steroid to use if one is in pursuit of more size and strength. Testosterone Cypionate promotes nitrogen retention in the muscle and the more nitrogen the muscles hold the more protein the muscles store. Testosterone Cypionate can also increase the levels of another anabolic hormone, IGF-1 in muscle tissue providing even more anabolic activity. Testosterone Cypionate also has the amazing ability to increase the activity of satellite cells. These cells play an active role in repairing damaged muscle. Testosterone also binds to the androgen receptor to promote androgen receptor dependent mechanisms for muscle gain and fat loss.
Testosterone Cypionate induces changes in shape, size and can also change the appearance and the number of muscle fibers. Androgens like testosterone can protect your hard earned muscle from the catabolic (muscle wasting) glucocorticoid hormones, in-turn inhibiting the related adverse reactions. In addition, Testosterone Cypionate has the ability to increase red blood cell production and a higher red blood cell count will improve endurance through increased oxygenation in the blood. More red blood cells can also improve recovery from strenuous physical activity. Even so, Testosterones anabolic/androgenic effects are dose dependent; the higher the dose the higher the muscle building effect.
Many athletes display massive strength gains while using Testosterone Cypionate as the hormone improves muscle contraction by increasing the number of motor neutrons in muscle and improves neuromuscular transmission. It also promotes glycogen synthesis providing more fuel for intense workouts thereby increasing endurance and strength.
Testosterone Cypionate also has the ability to promote fat loss through an enhancement of metabolic activity. Testosterone binds to the androgen receptor fairly well resulting in fat breakdown, and further prevents new fat cell formation. Another indirect action of fat loss that testosterone produces is the nutrient portioning effect it has on muscle and fat. Since the body is building muscle at an accelerated rate more of the food you eat is shuttled to muscle tissue instead of being stored as fat; nutrient efficiency is enhanced.
Testosterone Cypionate will also play a crucial role revolving around creatine. Creatine is essential to adenosine triphosphate (ATP), the source of energy for our muscles and when the muscles are stimulated ATP is broken down into adenosine diphosphate (ADP) and this is what releases energy. Unfortunately, the process is often too slow during strenuous activity but through the use of Testosterone Cypionate, this demand is met as ATP is replenished at a much faster rate.
With a well-planned Testosterone Cypionate cycle, nearly every anabolic steroid benefit can be obtained. For the off-season athlete, more lean muscle mass can be built with less body fat gain. In-order to grow, you must consume enough calories and fat gain will occur, but Testosterone Cypionate will ensure the brunt of your weight gain is the weight you want.
While off-season bulking use is the most common, the effects of Testosterone Cypionate can be tremendously beneficial during the cutting phase too. During this period of use, we are able to preserve far more lean muscle tissue that would otherwise be lost. In-order to lose body fat, we must burn more calories than we consume and this can and often does lead to muscle and strength loss. Further, the longer and harder you diet the more muscle and strength will be at risk, but due to the traits of Testosterone Cypionate muscle tissue and strength are protected.
Regardless of the purpose of use, Testosterone Cypionate defines performance enhancement by its ability to promote recovery and endurance. With a performance level dose of Testosterone Cypionate your body can recover faster and you wont tire out as quickly. This will allow you to workout longer and harder, and more progress can be made. This is performance enhancement at its best!
Testosterone Cypionate is only available in an injectable form and is regularly used to treat conditions such as low testosterone. More than twenty million men in the U.S. alone suffer from some form of low testosterone, and such a condition can severely diminish ones quality of life. Symptoms such as loss of muscle mass and strength, a decrease in libido and sexual performance, an increase in body fat, and low energy levels are all common characteristics of low testosterone. Further, when ignored low testosterone can be a gateway to Alzheimers, diabetes, osteoporosis and many other serious conditions. Most men will find one injection every seven to ten days at 100mg to 200mg per injection to completely eradicate such a problem.
For performance enhancement, one injection per week is often enough; however, in many cases two smaller yet equal sized injections will prove to be far more efficient. The reason for multiple injections is to keep blood levels peaked; further, it is often needed to control side effects that may occur with performance level dosing. Like most anabolic steroids, the more you take the greater the reward, but the more you take the greater the risk. By splitting the injections up into smaller more frequent injections, you are introducing smaller amounts of the hormone for your body to deal with all at once. As for the actual performance doses, this can range anywhere from 200mg per week all the way to 1,000mg per week depending on needs and desires.
The typical dose for those who are using Cypionate to counteract the lowering of testosterone due to the use of other steroids is normally 200mg. If it is being used for direct performance purposes, most will find 400mg to 600mg per week will be effective, but it is important to note that higher doses will greatly increase the risk.
Regardless of the total dose, most steroid users will find this to be an extremely well-tolerated anabolic steroid and one that can be used for long periods of time. 12 weeks of total use is quite commonplace, as is 16 weeks. There’s nothing magical about these numbers, but they are solid guidelines in-order for the individual to plan out his desired goals.
Regardless of the total dosing or the cycles length, you will need to design a post cycle therapy (PCT) plan once your Testosterone Cypionate use comes to an end. For most men, if you are discontinuing the use of anabolic steroids for more than ten weeks, you will need PCT but if your off period is less then it can be skipped. For full post cycle information and planning, please see the Post Cycle Therapy page on Steroid.com.
It should be noted; when it comes to performance enhancement, Testosterone Cypionate for women is not recommended. This is a steroid that carries far too much androgenic activity; after all, it is the primary male androgen. Women can suffer from low testosterone and there can be therapeutic benefits from the use of Testosterone Cypionate; however such treatment plans will be tremendously low dosed and should be watched closely for virilization symptoms.
As an extremely well-tolerated hormone for most men, the side effects of Testosterone Cypionate are in many ways easy to control. When it comes to such adverse reactions, keep in mind they largely fall into the realm of possible and are by no means guaranteed. Even so, total dosing, genetic predispositions and your overall state of health will play a role.
As for the side effects themselves, Testosterone Cypionate like all testosterone compounds carries a high level of aromatase activity; aromatization referring to the conversion of testosterone into estrogen. As estrogen levels rise, this can lead to gynecomastia (male breast enlargement) and excess water retention. This excess water retention can even negatively affect blood pressure. In-order to combat such effects, especially gynecomastia, many turn to Selective Estrogen Receptor Modulators (SERMs) such as Tamoxifen Citrate (Nolvadex) and for more serious protection Aromatase Inhibitors (AIs) such as Anastrozole (Arimidex). Without question, AIs are the most effective; however, they can also prove to be problematic when it comes to cholesterol and caution is advised.
Beyond these effects, Testosterone Cypionate can promote dihydrotestosterone (DHT) related side effects such as acne, hair loss and prostate enlargement; however, it should go without saying DHT steroids will be the prime culprits. In-order to provide protection, a 5-alpha reductase inhibitor such as Finasteride can be useful as it is an androgen suppressor and the androgen DHT is causing the problem. It must be noted; hair loss is only possible in men predisposed to male pattern baldness.
The drug Trenbolone is, without a doubt, the most powerful injectable anabolic steroid used by Steroid.com members to gain muscle. However the full properties of the drug are not always fully understood. This profile will separate fact from fiction and help steroid.com members decide if Trenbolone is right for them.
Trenbolone is similar to the highly popular steroid Nandrolone, in that they are both 19-nor steroids, meaning that a testosterone molecule has been altered at the 19th position to give us a new compound. Unlike Nandrolone however Trenbolone is an excellent mass and hardening drug with the majority of gains being muscle fiber, with minimal water retention (1) It has an unbelievable anabolic (muscle building) score of 500. When you compare that to Testosterone, which itself is a powerful mass builder, and has an anabolic score of 100 you can begin to fathom the muscle building potential of Trenbolone. What makes Trenbolone so anabolic? Numerous factors come into play. Trenbolone greatly increases the level of the extremely anabolic hormone IGF-1 within muscle tissue (2). And, its worth noting that not only does it increase the levels of IGF-1 in muscle over two fold, it also causes muscle satellite cells (cells that repair damaged muscle) to be more sensitive to IGF-1 and other growth factors(3). The amount of DNA per muscle cell may also be significantly increased (3).
Trenbolone also has a very strong binding affinity to the androgen receptor (A.R), binding much more strongly than testosterone (4). This is important, because the stronger a steroid binds to the androgen receptor the better that steroid works at activating A.R dependent mechanisms of muscle growth. There is also strong supporting evidence that compounds which bind very tightly to the androgen receptor also aid in fat loss. Think as the receptors as locks and androgen’s as different keys, with some keys (androgen’s) opening (binding) the locks (receptors) much better than others. This is not to say that AR-binding is the final word on a steroids effectiveness. Anadrol doesnt have any measurable binding to the AR& and we all know how potent Anadrol is for mass-building.
Trenbolone increases nitrogen retention in muscle tissue (5). This is of note because nitrogen retention is a strong indicator of how anabolic a substance is. However, it’s incredible mass building effects do not end there. Trenbolone has the ability to bind with the receptors of the anti-anabolic (muscle destroying) glucocorticoid hormones (6). This may also has the effect of inhibiting the catabolic (muscle destroying) hormone cortisol (7).
Yet another amazing trait that must be noted is its ability to improve feed efficiency and mineral absorption in animals given the drug (8). To help you understand what this means for you, feed efficiency is a measurement of how much of an animals diet is converted into meat, and the more food it takes to produce this meat, the lower the efficiency. Conversely, the less food it takes to produce meat the, higher the efficiency& well you get the idea. Animals given Trenbolone gained high quality weight without having their diet adjusted, thus improving feed efficiency. Finding new compounds which can improve feed efficiency is a billion dollar industry, and has spawned many nutritional advances in the bodybuilding world over the last few decades (CLA, Whey Protein, and HMB are compounds which spring to mind as having first been introduced by the livestock industry). What does this translate to for the hard training athlete? The food you eat will be better utilized for building lean muscle, and vitamins and minerals are also better absorbed which may keep you healthier during cycle.
10mL sterile multi-dose vial
The drug Trenbolone is, without a doubt, the most powerful injectable anabolic steroid used by Steroid.com members to gain muscle. However the full properties of the drug are not always fully understood. This profile will separate fact from fiction and help steroid.com members decide if Trenbolone is right for them.
Trenbolone is similar to the highly popular steroid Nandrolone, in that they are both 19-nor steroids, meaning that a testosterone molecule has been altered at the 19th position to give us a new compound. Unlike Nandrolone however Trenbolone is an excellent mass and hardening drug with the majority of gains being muscle fiber, with minimal water retention (1) It has an unbelievable anabolic (muscle building) score of 500. When you compare that to Testosterone, which itself is a powerful mass builder, and has an anabolic score of 100 you can begin to fathom the muscle building potential of Trenbolone. What makes Trenbolone so anabolic? Numerous factors come into play. Trenbolone greatly increases the level of the extremely anabolic hormone IGF-1 within muscle tissue (2). And, its worth noting that not only does it increase the levels of IGF-1 in muscle over two fold, it also causes muscle satellite cells (cells that repair damaged muscle) to be more sensitive to IGF-1 and other growth factors(3). The amount of DNA per muscle cell may also be significantly increased (3).
Trenbolone also has a very strong binding affinity to the androgen receptor (A.R), binding much more strongly than testosterone (4). This is important, because the stronger a steroid binds to the androgen receptor the better that steroid works at activating A.R dependent mechanisms of muscle growth. There is also strong supporting evidence that compounds which bind very tightly to the androgen receptor also aid in fat loss. Think as the receptors as locks and androgen’s as different keys, with some keys (androgen’s) opening (binding) the locks (receptors) much better than others. This is not to say that AR-binding is the final word on a steroids effectiveness. Anadrol doesnt have any measurable binding to the AR& and we all know how potent Anadrol is for mass-building.
Trenbolone increases nitrogen retention in muscle tissue (5). This is of note because nitrogen retention is a strong indicator of how anabolic a substance is. However, it’s incredible mass building effects do not end there. Trenbolone has the ability to bind with the receptors of the anti-anabolic (muscle destroying) glucocorticoid hormones (6). This may also has the effect of inhibiting the catabolic (muscle destroying) hormone cortisol (7).
Yet another amazing trait that must be noted is its ability to improve feed efficiency and mineral absorption in animals given the drug (8). To help you understand what this means for you, feed efficiency is a measurement of how much of an animals diet is converted into meat, and the more food it takes to produce this meat, the lower the efficiency. Conversely, the less food it takes to produce meat the, higher the efficiency& well you get the idea. Animals given Trenbolone gained high quality weight without having their diet adjusted, thus improving feed efficiency. Finding new compounds which can improve feed efficiency is a billion dollar industry, and has spawned many nutritional advances in the bodybuilding world over the last few decades (CLA, Whey Protein, and HMB are compounds which spring to mind as having first been introduced by the livestock industry). What does this translate to for the hard training athlete? The food you eat will be better utilized for building lean muscle, and vitamins and minerals are also better absorbed which may keep you healthier during cycle.
The drug Trenbolone is, without a doubt, the most powerful injectable anabolic steroid used by Steroid.com members to gain muscle. However the full properties of the drug are not always fully understood. This profile will separate fact from fiction and help steroid.com members decide if Trenbolone is right for them.
Trenbolone is similar to the highly popular steroid Nandrolone, in that they are both 19-nor steroids, meaning that a testosterone molecule has been altered at the 19th position to give us a new compound. Unlike Nandrolone however Trenbolone is an excellent mass and hardening drug with the majority of gains being muscle fiber, with minimal water retention (1) It has an unbelievable anabolic (muscle building) score of 500. When you compare that to Testosterone, which itself is a powerful mass builder, and has an anabolic score of 100 you can begin to fathom the muscle building potential of Trenbolone. What makes Trenbolone so anabolic? Numerous factors come into play. Trenbolone greatly increases the level of the extremely anabolic hormone IGF-1 within muscle tissue (2). And, its worth noting that not only does it increase the levels of IGF-1 in muscle over two fold, it also causes muscle satellite cells (cells that repair damaged muscle) to be more sensitive to IGF-1 and other growth factors(3). The amount of DNA per muscle cell may also be significantly increased (3).
Trenbolone also has a very strong binding affinity to the androgen receptor (A.R), binding much more strongly than testosterone (4). This is important, because the stronger a steroid binds to the androgen receptor the better that steroid works at activating A.R dependent mechanisms of muscle growth. There is also strong supporting evidence that compounds which bind very tightly to the androgen receptor also aid in fat loss. Think as the receptors as locks and androgen’s as different keys, with some keys (androgen’s) opening (binding) the locks (receptors) much better than others. This is not to say that AR-binding is the final word on a steroids effectiveness. Anadrol doesnt have any measurable binding to the AR& and we all know how potent Anadrol is for mass-building.
Trenbolone increases nitrogen retention in muscle tissue (5). This is of note because nitrogen retention is a strong indicator of how anabolic a substance is. However, it’s incredible mass building effects do not end there. Trenbolone has the ability to bind with the receptors of the anti-anabolic (muscle destroying) glucocorticoid hormones (6). This may also has the effect of inhibiting the catabolic (muscle destroying) hormone cortisol (7).
Yet another amazing trait that must be noted is its ability to improve feed efficiency and mineral absorption in animals given the drug (8). To help you understand what this means for you, feed efficiency is a measurement of how much of an animals diet is converted into meat, and the more food it takes to produce this meat, the lower the efficiency. Conversely, the less food it takes to produce meat the, higher the efficiency& well you get the idea. Animals given Trenbolone gained high quality weight without having their diet adjusted, thus improving feed efficiency. Finding new compounds which can improve feed efficiency is a billion dollar industry, and has spawned many nutritional advances in the bodybuilding world over the last few decades (CLA, Whey Protein, and HMB are compounds which spring to mind as having first been introduced by the livestock industry). What does this translate to for the hard training athlete? The food you eat will be better utilized for building lean muscle, and vitamins and minerals are also better absorbed which may keep you healthier during cycle.