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10mL sterile multi-dose vial
Clenbutero Hydrochloride is a powerful bronchodilator that is used to treat breathing disorders like asthma. While it’s been extremely successful in such treatment plans it has never been approved by the U.S. FDA. It is, however, approved and used in most other countries around the world. Some speculate the only reason Clenbuterol has never been approved by the U.S. FDA is due to there being no need. There are several other related medications, very closely related that are already approved for U.S. use.
Beyond treating breathing disorders, Clenbuterol is commonly used as a thermogenic. In fact, you will more than likely find more Clenbuterol use in fat loss plans than anywhere else. It is a very common fat burning tool used by many anabolic steroid users. It is a long standing favorite among competitive bodybuilders and other physique athletes during contest preparation. However, it is also used by non-steroid users for its fat loss properties. You do not have to use anabolic steroids to use this compound for fat loss. We only mention that because this has for some reason become a confusing point for some.
Clenbuterol Hydrochloride is a sympathomimetic that works on the sympathomimetic nervous system. There are several receptors in the body a sympathomimetic can act on. In the case of Clenbuterol, the beta-2 receptor is the area of interest and action. Clen, as it’s commonly known, actively stimulates the beta-2 receptor. Through such stimulation, this actively reverses airway obstructions and provides improved breathing for those who need it. This same stimulation can also be used to enhance the metabolic rate of the individual. Clenbuterol does not actively burn fat by attacking fat cells, but rather stimulates the metabolism by increasing the body’s temperature. This occurs due to the beta-2 stimulation stimulating the mitochondria of the cells to produce and release more heat. In turn, this heats up the body’s temperature (slightly), enhances the metabolism and causes the individual to burn body fat at a greater rate. In reality, the functions and traits of Clenbuterol are very simple and very straightforward.
Clenbuterol has also been noted for having a strong anabolic effect; however, things are not quite like they appear. Due to the potential anabolic effect, this has caused many to use the compound in hopes of gaining lean tissue. Commonly, many steroid users have used it as an anabolic protective agent during their post cycle therapy (PCT). There is, however, a problem with this type of use; it doesn’t work. Studies have shown that Clenbuterol has the ability to promote anabolic activity in animals. There have been several studies that have shown the anabolic activity of rats to increase when Clen is administered. However, there is no data that supports such anabolic activity provided when used by human beings. In fact, it has generally been proven useless in this regard as it pertains to human beings. When it comes to human Clenbuterol use, use as a bronchodilator and thermogenic are the only suitable purposes.
The effects of Clenbuterol on the asthmatic patient are as straightforward as can be. Use of the bronchodilator opens up the airways and enables the individual to breath. There are other breathing disorders that can benefit from Clenbuterol use, but asthma appears to be primary, and it is often a welcomed medication to those who suffer. This same improved breathing could also prove useful to some athletes, especially those who can benefit from enhanced cardiovascular endurance. However, we’re not talking about a strong, notable improvement and there are truly other methods that are far more suited for increasing cardiovascular endurance.
As a thermogenic, the effects of Clenbuterol are again very simple. As the body temperature increases, which again is due to the beta-2 stimulation, the individual is now able to burn calories at an enhanced rate. Body temperature goes up, the metabolism is enhanced, fat cells are stimulated due to the increase in temperature due to the now enhanced metabolism, the breakdown of triglycerides is now enhanced and fat loss occurs. It’s hard to get any simpler than that.
While Clenbuterol is a powerful fat loss agent, it is not magical and will not make a fat physique lean on its own. You still have to diet in order to lose body fat, and if you don’t, no fat loss will occur. In fact, even if you’re using Clenbuterol you will still find you need to diet just as hard as you would without it if you are going to lose body fat. This raises an important question; why use Clen? The idea behind Clenbuterol use as a thermogenic in simple terms it to take what you’re already doing right and to simply do it a little better. It’s not going to melt fat off your frame, but it can rev up the metabolism and help you burn fat at a more effective and efficient rate. If you are obese or at least significantly overweight, your best bet is to forgo Clenbuterol use until you are at least a little leaner. The best time to use Clen is once you’re already fairly lean in an effort to help you rid that last little body fat that often hangs on for dear life. When we dive into the side effects of Clenbuterol, we will find Clen can and should only be used for a set period of time, and it only makes sense to use it when it will be the most beneficial.
Due to Clenbuterol being best served for final touches in a fat loss plan, this is why you’ll see it in many physique based plans such as bodybuilding, figure, fitness or other related endeavors. It’s commonly used the last 8-10 weeks leading up to a competition, sometimes a little longer, but regardless of the specific time frame the individual is normally already fairly lean. For the average gym rat, one who doesn’t compete but is looking to lean out, we can make some slight exceptions. We’re not saying you have to be contest ready lean in order for their to be a benefit. If you’re already in fairly good shape and looking to lean out a little more, absolutely, Clenbuterol can prove useful. But if you truly have a lot of body fat to lose, you’ll be best served by waiting until your body fat is a little more under control.
There are several possible side effects to Clenbuterol use, and the primary will surround its stimulating nature. No surprise, after all, Clen is a stimulant. The side effects of Clenbuterol can be very strong and often very annoying to say the least, and they will generally affect most people in one way or another. The most common side effects surround a jittery or wired feeling, shaky hands and increased sweating. Most all who use Clen will experience such effects to a degree, but they will commonly be very pronounced during the early stages of use. As the individual becomes accustomed to the stimulant, such related effects should begin to subside, but they will be so strong in some people that some will not be able to use it.
When using Clenbuterol, many often inaccurately assume that when the stimulating effects of Clen began to fade that the thermogenic effects are no longer working. Most will find that the stimulating effects will greatly subside after a week or so of use, but assuming the fat burning properties have vanished due to this lessened stimulation is highly inaccurate. The same dose of Clenbuterol Hydrochloride can actually keep the metabolism revved for as much as five weeks. Granted, by the fifth week mark it will be minimal as the body does most certainly adapt. Due to the body’s ability to adapt, necessarily adjustments must be made to use. We will go over adjustments, dosing plans and total plans of use in the Clenbuterol in the administration section.
The aforementioned side effects of Clenbuterol are the most common, but there are other possible effects of note. As with many stimulating substances, some will experience headaches as well as possible nausea. One of the more bothersome possible side effects of Clenbuterol Hydrochloride will be muscle cramps. Cramps are not exceedingly common, but they will affect many people. Athletes are often at the greatest risk due to the hard and often intense training they are already undertaking. Staying well hydrated is often enough to avoid or remedy this problem, but supplementing with taurine can also help. Clen has been shown to deplete taurine, so supplementation may be necessary for some. Some may also have issues with insomnia; in fact, some may find sleep becomes extremely difficult. Again, this is very common with many stimulating substances, but with Clen it can, for some, be impossible to avoid. Clen has an active half-life that stretches to the 34 hour mark, and that can make sleep impossible for some people. Many will, however, find if they take their Clen first thing in the morning they will not have any issues with sleep, but due to the long half-life some will find insomnia occurs regardless of when they take it.
The use of Clenbuterol Hydrochloride also carries with it possible side effects that can be severe; in fact, dangerous would be a more accurate description. Such effects are most commonly associated with abuse through high doses and far beyond recommended extended periods of use. The severe side effects of Clenbuterol include high blood pressure, irregular heartbeat, trembling and even panic. Some studies have also shown that Clenbuterol abuse can also lead to cardiac hypertrophy, which could potentially lead to death. It is very possible to use this compound without such effects, but as with so many things in life it will require responsible use and a thorough understanding of Clen.
In a therapeutic setting, Clenbuterol doses will most commonly be 20mcg per day, with some requiring 40mcg per day. It is possible for some to need even more, but it is rare and generally only for a short period of time. This should, in most all cases, be enough Clen to correct related breathing issues, if not, alternative treatments may be needed.
In a performance setting as a thermogenic, Clenbuterol doses will start low and generally increase overtime due to a down regulation of the beta-receptor. Most men will find starting at 40mcg per day to be perfect. Many women may also be fine with this starting dose, but many will be far more comfortable with a starting dose of 20mcg per day. As the body adapts, the dose will need to increase in order to maintain the full fat loss benefits. There are several schools of thought on the best way to use Clen in a fat burning setting, but there are only three that really make any sense. All three will work very well, but you may need to try all three at separate times to find which one works best for you.
One of the most common methods of Clenbuterol use for fat loss purposes is two weeks on followed by two weeks off. This type of use will normally continue until the end goal is reached. The individual will start with the initial dose and increase it by 20mcg every few days until he has reached the maximum desired or needed dose. The individual will then hold at this dose the final days of the two week period and then discontinue all Clenbuterol use for two weeks. At the end of the two weeks with no Clen, the individual will begin the process again.
The two week rotation schedule is very effective, but there is also a problem. During the off periods you have no Clen in your system, and as a result, a two week period with a decreased metabolic rate. This does not mean you won’t be burning fat during the off week periods, as long as you’re dieting you should still lose fat, but you are giving up the enhancement.
Due to the body’s ability to adapt to Clenbuterol, continuous use is very hard for some to get their head around. When we consider that the stimulating effects of a noticeable nature began to wane first, the idea of continuous use for some doesn’t make any sense, but we assure you this method of use can work very well. Remember, the same dose of Clen can keep the metabolism revved for up to 5 weeks.
With this type of use, the individual will begin with the starting dose of 20-40mcg per day and hold at that dose for 2-3 weeks. At the end of the 2-3 week period, the individual will increase the dose by 20mcg and hold at that dose for another 2-3 weeks. From here, the individual will increase the dose 20mcg every 2-3 weeks as needed until the diet or total Clen use comes to an end. This type of use will keep your metabolism revved the entire time. It may not experience as great of an increase as would with a massive or very frequent increasing in dose schedule, but it will be a steady and continuous enhancement. There will be no period in the diet during Clenbuterol use that the individual doesn’t enjoy the metabolic enhancement.
The final preferred method of Clenbuterol use falls in-between our other two discussed methods. This type of use will last for 4-6 weeks and can be an excellent way to use it for the individual who is only using it the last few weeks leading up to competition. The individual will start with 40mcg per day and increase periodically until he reaches the maximum desired or needed dose and will hold at the maximum dose the final 7-14 days of the plan. The increases in dosing will not be as dramatic as the two week rotation schedule but stronger than the continuous plan. At this stage, if more Clen is still needed, the individual will need to wait 4-6 weeks before beginning a new phase. This makes this type of use best for those who only need a short period of metabolic enhancement.
Regardless of the type of schedule you use, the maximum Clenbuterol dose will normally be 120mcg per day. Some may find 140mcg per day to be acceptable, especially some men, but no one should for any reason surpass the 140mcg per day mark if they are going to avoid cardiac damage. Regardless of the total dosing or plan of use you use, Clenbuterol use should be kept at no more than 16 weeks of total use. 16 weeks of total use per year should be your guide. For the individual competing in more than one show per year at different stages of the year, we can make exceptions. However, this individual should try to keep the total use as close to a 16 week total every 12 months as possible for safety reasons
Dianabol represents one of the most popular and one of the most important anabolic steroids of all time. Without question, this is the most popular oral steroid to ever hit the market and one of the most popular steroids in any form. While almost always found as an oral tablet, Dianabol can be found as an injectable solution, but the tablets represent the primary route of administration. Why is this steroid so important? In many ways it gave birth to the age of modern performance enhancement. It was not the first anabolic steroid used for that purpose, that would belong to testosterone, but Dianabol would open the door to a new wave of steroid use that has grown beyond what anyone expected.
Dianabol represents one of the only anabolic steroids that was developed for the sole purpose of performance enhancement. The compound did carry listed therapeutic uses at one time, but performance was the true reason this steroid was given life. Through the 1940’s and 50’s the Soviet Union had begun to dominate the Olympic games, and the use of testosterone by many of its athletes left the rest of the world lagging far behind. During this time, U.S. Olympic team Dr. John Ziegler would learn of the U.S.S.R.’s steroid use, and quickly would aid in ensuring his athletes would match up. In 1958, with the help of Dr. Ziegler, Ciba Pharmaceuticals would release the first batches of Methandrostenolone under the trade name Dianabol. The compound was designed in an effort to maintain the anabolic properties of testosterone with less androgenicity in a fast acting, powerful method. Seemingly overnight the steroid was a massive success, giving many U.S. athletes a distinct advantage over their Soviet rivals.
After its inception, Dianabol would quickly find its way into nearly every competitive sport imaginable. In conjunction with exogenous testosterone, this would birth an age of performance unlike the world had ever seen. The steroid would also rapidly become a staple in competitive bodybuilding where it has remained a favorite to this day. However, shortly after its release the U.S. FDA would begin to put a lot of pressure on Ciba in an effort to push the company to list true medical benefits of the steroid. The FDA would approve its use for the treatment osteoporosis in post-menopausal women as well as pituitary-deficient dwarfism, but the latter was withdrawn in the early 1980’s. Again the FDA would pressure Ciba for more information, but in 1983 under mounting pressure Ciba would discontinue the Dianabol tab. A few years later, the FDA would pull all Methandrostenolone brands from the shelf. Since that time Dianabol has not been legally manufactured in the United States, but is still manufactured heavily all over the world.
Methandrostenolone is a testosterone derived anabolic androgenic steroid. Officially, it is a structurally altered form of the primary male androgen testosterone. Dianabol is the testosterone hormone with an added double bond at the carbon one and two position. This slight alteration reduces the hormone’s androgenic nature. It also carries an added methyl group at the 17th carbon position that allows the hormone to survive oral ingestion, officially classifying Dianabol as a C17-alpha alkylated steroid. An important note, injectable Dianabol is also C17-alpha alkylated. The end result gives us an anabolic steroid with an androgenic rating of 40-60 with a much lower binding affinity to the androgen receptor compared to testosterone. However, it will also share a much weaker relationship for serum binding protein, which results in an extremely powerful anabolic steroid. If there’s any doubt, this is one extremely powerful anabolic steroid carrying a potent anabolic nature.
On a functional basis, Dianabol is one of the easier anabolic steroids to understand. This steroid will largely provide its anabolic benefits by enhancing protein synthesis, nitrogen retention and glycogenolysis. Protein synthesis represents the rate by which cells build proteins, the building blocks of muscle. Nitrogen retention, this is important as all muscle tissue is comprised of approximately 16% nitrogen. The more nitrogen we retain, the more anabolic we remain. Conversely, a nitrogen deficiency results in a catabolic or muscle wasting state. Then we’re left with glycogenolysis, which refers to the relationship and conversion between glycogen and glucose. Through enhanced glycogenolysis, we are able to make better use of our total carbohydrate consumption. While in many ways these traits are quite simple, they are strong enough to make Dianabol a remarkably powerful anabolic steroid.
Another important trait of Dianabol and perhaps one of the most important of all is the relationship it shares with other anabolic steroids. Dbol as it’s often called is not what we’d label as a base steroid. This is not an anabolic steroid we build a cycle around, but rather one we add to a well-planned stack. Dianabol has the ability to create unbelievable synergy when conjoined with other anabolic steroids. For example, you could supplement with 100mg of Trenbolone, Masteron or Equipoise per day (doses and steroids are simply being used as an example, not actual recommendations) and the results you’d receive from 50mg per day of Trenbolone, Masteron or Equipoise along side 50mg of Dianabol per day would be far more dramatic. You would have an identical amount of total milligrams of anabolic steroids with or without Dianabol, but the added Dianabol would provide greater enhancement.
The effects of Dianabol can be summed up as fast acting and dramatic. In fact, it is more than possible for the individual to gain as much as 20lbs of mass in only a few weeks of Dianabol use. Total dosing will play a role, as will total caloric consumption, but a 20lb gain is very realistic. This makes Dianabol a premier off-season bulking steroid, and that will be its most common purpose of use. During this phase of use, the individual should also expect his strength to increase significantly. Dbol is actually one of the best strength increasing steroids on the market and along with mass can produce this result rapidly.
The effects of Dianabol are also greatly appreciated by many athletes; however, it is not as common as it once was in athletic enhancement circles. Due to the possible rapid increases in mass, many athletes will opt for steroids like Anavar or Winstrol, but it generally depends on the purpose of use. Due to the rapid and pronounced increases in strength, which can translate into more power and speed, this can be a solid athletic enhancer. The individual should also experience a level of enhanced recovery and endurance. When it comes to the weight gain, it’s important to remember that this will largely revolve around total caloric intake. While the steroid can promote enormous amounts of mass, you have to feed the body enough calories to reach this end. We wouldn’t call this the best athletic enhancing steroid due to other options, but if strength is the only true concern it could be a decent option.
Then we’re left with the cutting cycle, and you will not find Dianabol in such plans too often. Some competitive bodybuilders will use it early on in a cutting phase in order to maintain fullness, and it will provide lean tissue protection; however, there are better options. One problem with cutting cycle use can be the level of water retention this steroid can provide, which is normally the last thing you want when cutting. Such retention can be controlled, and the ability for this steroid to maintain strength can be appreciated, but there are better options.
There are several possible side effects of Dianabol use. This is not the most dangerous anabolic steroid of all time, but it can carry a host of potential problems. A healthy adult male can manage the side effects of Dianabol, but you must understand them and how to combat them to pull this off. In order to achieve successful supplementation, we have broken down the possible side effects of Dianabol into their related categories along with all you need to know
Boldenone Undecylenate is a testosterone derived anabolic androgenic steroid that is best known by the trade name Equipoise given to it by Squibb in the 1970’s. While Equipoise is officially classified as a veterinarian grade anabolic steroid, the first batches of Boldenone were introduced on the human grade pharmaceutical market by Ciba in the early 1950’s under the brand name Parenabol. Human grade Boldenone would see some success in human medicine through the 1960’s and 70’s but would ultimately be discontinued by the end of the decade. Since that time, the steroid has only been available through veterinarian medicine and underground labs with the Equipoise name dominating the market. Fort Dodge Animal Health now owns the Equipoise name.
For decades, it has been assumed that Equipoise was very similar to Deca Durabolin (Nandrolone Decanoate). This assumption was in part based on comments the late Dan Duchaine made about the steroid. However, the two compounds are not similar in any way; in fact, Duchaine would recant the statement, but the initial statement has been enough to keep the rumor alive. If Equipoise shares anything in common with another anabolic steroidal hormone, it would be testosterone, but EQ as it’s commonly known is unique in its own right. An important note regarding the differences in these two steroidal hormones; Nandrolone carries a strong progestin nature, while Boldenone carries no progestin characteristics.
Equipoise (Boldenone Undecylenate) is a structurally altered form of testosterone. It is a very slight change in an added double bond at the carbon one and two position. This double bond greatly reduces the hormone’s androgenicity, as well as estrogenic nature. It is then attached to the very large or long Undecylenate ester, which is responsible for controlling the release of the hormone once administered into the body. The Undecylenate ester allows for a peak release in Boldenone approximately 3-4 days after injection, with a slow continuous release of the hormone to follow for approximately 21 days.
Due to its structural change, Equipoise only aromatizes at approximately 50% the rate of testosterone. Estrogenic side effects are possible, but the odds are highly in the individual’s favor compared to testosterone. It is not as powerful of a mass builder as testosterone, not even close, but the reduced estrogenic activity should allow the individual to make cleaner gains through supplementation.
Equipoise shares many similarities regarding direct enhancement properties with testosterone. Common shared properties include its ability to enhance protein synthesis, nitrogen retention in the muscles, inhibit glucocorticoid hormones and increase IGF-1 output. Equipoise is also well known for increasing red blood cell count, a trait shared by most all anabolic steroids. However, issues of concern have been noted regarding how much Equipoise can increase red blood cell count. But available data tends to support this only being a concern with extremely high dose use for extremely long periods of time. In many ways, the increase in red blood cells provided by Equipoise can be fast and rapid, but may not present a significant advantage or disadvantage compared to most anabolic steroids when used responsibly. Without question, a moderate increase in cell production would be very advantageous for most any athlete.
The effects of Equipoise are fairly straightforward. This is a generally well-tolerated anabolic steroid that presents notable anabolic activity in most users in a clean and even fashion. Outside of performance enhancement use, Boldenone did enjoy some success as a human grade steroid for a time. The steroid had some success in treating muscle wasting diseases and osteoporosis, but would ultimately give way to other steroidal options. As a veterinarian steroid, Equipoise is well-known for its use in horses, hence the name “Equipoise” and its similarity to the word “Equestrian.” EQ is often given to horses in an effort to increase lean body weight, which is in part due to the steroid’s ability to increase appetite. An increased appetite is well noted among many performance enhancing athletes that use Equipoise, however, it doesn’t appear to affect everyone the same. Many who use the anabolic steroid report no increase in appetite, it tends to be highly individualistic, but it could be useful for those struggling to consume needed calories.
As an off-season bulking steroid, Equipoise can add quality lean mass gains, but they will not come overnight, and will fall short of many anabolic steroids. Steroids like Deca Durabolin will produce far greater mass results, as will steroids like Anadrol and Dianabol; however, the latter two are often accompanied by large amounts of water retention. Some athletes have, however, reported stronger off-season gains when Equipoise is added to a total off-season stack rather than used as a base steroid. If appetite suppression is an issue, this steroid may very well help you consume the excess calories needed for off-season growth. Of course, while it may not be a tremendous mass building steroid, for some it may produce all the mass they want. Not everyone who uses anabolic steroids is looking for immense gains in size.
Equipoise is also well-noted for promoting increases in strength. An increase in strength can be very beneficial to an off-season mass plan, but perhaps more beneficial to the enhancement of athletic performance. Unfortunately, the extremely long detection time will prohibit many athletes from using EQ. Total detection time can stretch to five months. However, the steroid definitely provides numerous advantages to the athlete, not only in an increase in strength but a notable increase in muscular endurance. Recovery should also be enhanced. Regardless of the desired purpose of use, all who supplement with Equipoise will enjoy these related benefits.
Equipoise can also be used as a cutting steroid; in fact, this may be the most beneficial point of use. This anabolic steroid is an excellent protectant of lean muscle mass. In order to lose body fat, you must burn more calories than you consume, you must be in a caloric deficit, and this will hold true with or without anabolic steroid use. Unfortunately, a calorie deficit puts our lean muscle tissue at risk as the body will often take what it needs in order to meet its energy demands from our lean tissue. Proper dieting can greatly protect our lean muscle mass, but it can only go so far. Without the introduction of an anabolic steroid, some muscle mass will eventually and inevitably be lost. EQ will greatly protect you from this loss in lean tissue, and it has also been shown to have some very nice conditioning effects on the physique. Such effects will be greatly enhanced when combined with a non-aromatizing steroid like Masteron (Drostanolone) or Trenbolone. However, during most cutting plans of a competitive bodybuilding nature, while EQ is commonly used it is normally only used at the frontend of the cutting cycle. It will normally be discontinued during the later half of the plan due to possible estrogenic activity. While total estrogenic activity should be low, during this phase of supplementation any and all estrogenic activity is normally avoided or at least minimized to the lowest point possible.
Equipoise is a generally well-tolerated anabolic steroid for most men, and is often very well-tolerated by many women when low doses are applied. Side effects of Equipoise use are certainly possible, but most healthy adults should find this anabolic steroid very manageable. In order to help you understand the possible side effects of Equipoise use as well as their management, we have broken them down into their specific categories along with all the related information you’ll need.
Dianabol represents one of the most popular and one of the most important anabolic steroids of all time. Without question, this is the most popular oral steroid to ever hit the market and one of the most popular steroids in any form. While almost always found as an oral tablet, Dianabol can be found as an injectable solution, but the tablets represent the primary route of administration. Why is this steroid so important? In many ways it gave birth to the age of modern performance enhancement. It was not the first anabolic steroid used for that purpose, that would belong to testosterone, but Dianabol would open the door to a new wave of steroid use that has grown beyond what anyone expected.
Dianabol represents one of the only anabolic steroids that was developed for the sole purpose of performance enhancement. The compound did carry listed therapeutic uses at one time, but performance was the true reason this steroid was given life. Through the 1940’s and 50’s the Soviet Union had begun to dominate the Olympic games, and the use of testosterone by many of its athletes left the rest of the world lagging far behind. During this time, U.S. Olympic team Dr. John Ziegler would learn of the U.S.S.R.’s steroid use, and quickly would aid in ensuring his athletes would match up. In 1958, with the help of Dr. Ziegler, Ciba Pharmaceuticals would release the first batches of Methandrostenolone under the trade name Dianabol. The compound was designed in an effort to maintain the anabolic properties of testosterone with less androgenicity in a fast acting, powerful method. Seemingly overnight the steroid was a massive success, giving many U.S. athletes a distinct advantage over their Soviet rivals.
After its inception, Dianabol would quickly find its way into nearly every competitive sport imaginable. In conjunction with exogenous testosterone, this would birth an age of performance unlike the world had ever seen. The steroid would also rapidly become a staple in competitive bodybuilding where it has remained a favorite to this day. However, shortly after its release the U.S. FDA would begin to put a lot of pressure on Ciba in an effort to push the company to list true medical benefits of the steroid. The FDA would approve its use for the treatment osteoporosis in post-menopausal women as well as pituitary-deficient dwarfism, but the latter was withdrawn in the early 1980’s. Again the FDA would pressure Ciba for more information, but in 1983 under mounting pressure Ciba would discontinue the Dianabol tab. A few years later, the FDA would pull all Methandrostenolone brands from the shelf. Since that time Dianabol has not been legally manufactured in the United States, but is still manufactured heavily all over the world.
Methandrostenolone is a testosterone derived anabolic androgenic steroid. Officially, it is a structurally altered form of the primary male androgen testosterone. Dianabol is the testosterone hormone with an added double bond at the carbon one and two position. This slight alteration reduces the hormone’s androgenic nature. It also carries an added methyl group at the 17th carbon position that allows the hormone to survive oral ingestion, officially classifying Dianabol as a C17-alpha alkylated steroid. An important note, injectable Dianabol is also C17-alpha alkylated. The end result gives us an anabolic steroid with an androgenic rating of 40-60 with a much lower binding affinity to the androgen receptor compared to testosterone. However, it will also share a much weaker relationship for serum binding protein, which results in an extremely powerful anabolic steroid. If there’s any doubt, this is one extremely powerful anabolic steroid carrying a potent anabolic nature.
On a functional basis, Dianabol is one of the easier anabolic steroids to understand. This steroid will largely provide its anabolic benefits by enhancing protein synthesis, nitrogen retention and glycogenolysis. Protein synthesis represents the rate by which cells build proteins, the building blocks of muscle. Nitrogen retention, this is important as all muscle tissue is comprised of approximately 16% nitrogen. The more nitrogen we retain, the more anabolic we remain. Conversely, a nitrogen deficiency results in a catabolic or muscle wasting state. Then we’re left with glycogenolysis, which refers to the relationship and conversion between glycogen and glucose. Through enhanced glycogenolysis, we are able to make better use of our total carbohydrate consumption. While in many ways these traits are quite simple, they are strong enough to make Dianabol a remarkably powerful anabolic steroid.
Another important trait of Dianabol and perhaps one of the most important of all is the relationship it shares with other anabolic steroids. Dbol as it’s often called is not what we’d label as a base steroid. This is not an anabolic steroid we build a cycle around, but rather one we add to a well-planned stack. Dianabol has the ability to create unbelievable synergy when conjoined with other anabolic steroids. For example, you could supplement with 100mg of Trenbolone, Masteron or Equipoise per day (doses and steroids are simply being used as an example, not actual recommendations) and the results you’d receive from 50mg per day of Trenbolone, Masteron or Equipoise along side 50mg of Dianabol per day would be far more dramatic. You would have an identical amount of total milligrams of anabolic steroids with or without Dianabol, but the added Dianabol would provide greater enhancement.
The effects of Dianabol can be summed up as fast acting and dramatic. In fact, it is more than possible for the individual to gain as much as 20lbs of mass in only a few weeks of Dianabol use. Total dosing will play a role, as will total caloric consumption, but a 20lb gain is very realistic. This makes Dianabol a premier off-season bulking steroid, and that will be its most common purpose of use. During this phase of use, the individual should also expect his strength to increase significantly. Dbol is actually one of the best strength increasing steroids on the market and along with mass can produce this result rapidly.
The effects of Dianabol are also greatly appreciated by many athletes; however, it is not as common as it once was in athletic enhancement circles. Due to the possible rapid increases in mass, many athletes will opt for steroids like Anavar or Winstrol, but it generally depends on the purpose of use. Due to the rapid and pronounced increases in strength, which can translate into more power and speed, this can be a solid athletic enhancer. The individual should also experience a level of enhanced recovery and endurance. When it comes to the weight gain, it’s important to remember that this will largely revolve around total caloric intake. While the steroid can promote enormous amounts of mass, you have to feed the body enough calories to reach this end. We wouldn’t call this the best athletic enhancing steroid due to other options, but if strength is the only true concern it could be a decent option.
Then we’re left with the cutting cycle, and you will not find Dianabol in such plans too often. Some competitive bodybuilders will use it early on in a cutting phase in order to maintain fullness, and it will provide lean tissue protection; however, there are better options. One problem with cutting cycle use can be the level of water retention this steroid can provide, which is normally the last thing you want when cutting. Such retention can be controlled, and the ability for this steroid to maintain strength can be appreciated, but there are better options.
There are several possible side effects of Dianabol use. This is not the most dangerous anabolic steroid of all time, but it can carry a host of potential problems. A healthy adult male can manage the side effects of Dianabol, but you must understand them and how to combat them to pull this off. In order to achieve successful supplementation, we have broken down the possible side effects of Dianabol into their related categories along with all you need to know:
Dianabol is a relatively strong estrogenic anabolic steroid due to the moderate level of aromatase activity it carries. While its aromatase activity is only moderate, this conversion actually leads Methandrostenolone to be converted to methylestradiol rather than estradiol, which is far more powerful than estradiol. This can make side effects like gynecomastia and water retention very possible with this steroid; in fact, they can appear seemingly overnight. Heavy water retention can also promote high blood pressure, which Dianabol is notorious for causing. Such effects can be controlled, and when it comes to high blood pressure this is something you’ll need to put some effort into ensuring does not become a problem.
In order to combat the estrogenic side effects of Dianabol, anti-estrogens are commonly recommended when supplementing with this steroid. You have two choices in anti-estrogens, Selective Estrogen Receptor Modulators (SERM’s) like Nolvadex (Tamoxifen Citrate) and Aromatase Inhibitors (AI’s) like Femara (Letrozole). SERM’s can be enough for some men and should be your first choice if they can get the job done. However, AI’s will be far more effective as they will directly inhibit aromatization and reduce serum estrogen levels. Unfortunately, AI’s can negatively affect cholesterol, as can Dianabol, and when conjoined this can prove potentially problematic. If an AI is used cholesterol management will be a priority, and it will be possible. However, SERM’s, while not always as effective will actually promote healthier cholesterol levels due to their estrogenic like activity in the liver.
Dianabol is not an extremely androgenic steroid, its androgenicity has been structurally reduced, but androgenic side effects are still possible. Such side effects of Dianabol use include acne, accelerated hair loss in those predisposed to male pattern baldness and body hair growth. Most men should not have a problem with such effects, response will be the final dictator, but most will remain clear. Although the odds are in your favor, such effects are brought on by Methandrostenolone being metabolized by the 5-alpha reductase enzyme. This is the same enzyme responsible for the reduction of testosterone to dihydrotestosterone, but the overall conversion here will result in very low amounts of dihydromethandrostenolone. This tells us 5-alpha reductase inhibitors like Finasteride that are often used to combat androgenic side effects will have very little if any affect on Dianabol.
Despite its reduced androgenicity, Dianabol can promote virilization symptoms in women. Such symptoms include body hair growth, a deepening of the vocal chords and clitoral enlargement. It is possible for some women to use this steroid without virilization symptoms with extremely low doses, but the odds are not favorable. Most all women should choose anabolic steroids with less translating androgenic activity to meet their needs.
Dianabol can have a pronounced negative effect on cholesterol. This includes HDL cholesterol suppression and increases in LDL cholesterol, and the total changes can be significant. It is possible for total cholesterol levels to remain in a healthy range, but it is also possible for this healthy total reading to be misleading if HDL is suppressed heavily. Managing cholesterol during Dianabol use will be extremely important. Repeated use of this steroid as with many anabolic steroids could potentially lead to plaque buildup in the arteries overtime. It’s also extremely important to keep in mind the very possible additional strain on cholesterol brought on by the use of an AI when supplementing with Dianabol as total estrogen reductions will have a negative effect. Again, cholesterol maintenance will be extremely important.
As discussed, Dianabol can also play a negative role on blood pressure, which can be controlled by controlling water retention in most cases. When it comes to the blood pressure and cholesterol issues, the ultimate key to success will be your lifestyle. You should not supplement with this steroid if you already suffer from high blood pressure or cholesterol. If you are healthy enough for use, you should ensure your lifestyle is conducive to their maintenance. This should include a healthy diet that is rich in omega fatty acids, plenty of cardiovascular activity and an avoidance of any activity that promotes the opposite, negative end. Proper estrogen maintenance and control will also be important as estrogen plays an important role in cholesterol management. Yes, it is more than possible to supplement with Dianabol without high blood pressure and cholesterol, but you must put in the effort.
All anabolic steroids suppress natural testosterone production. While the total rate of suppression varies from one steroid to the next, with Dianabol it is very pronounced. For this reason, most men are encouraged to include some form of exogenous testosterone with their Dianabol use. Failure to include exogenous testosterone, regardless of your genetics or rumors you have heard will lead to a low testosterone condition. Such a condition comes with a host of possible symptoms and is extremely unhealthy. Even if symptoms do not show or are moderate at best, a low level condition will remain an unhealthy one. If you include exogenous testosterone, this problem is solved as the body will have all the testosterone it needs.
Once the use of Dianabol is complete and all the exogenous steroidal hormones have cleared your system, natural testosterone recovery will begin again. Natural recovery assumes no prior low testosterone condition. It also assumes no damage was done to the Hypothalamic-Pituitary-Testicular-Axis (HPTA) due to improper anabolic steroid use. While natural recovery will begin on its own, it will be slow. For this reason, most are encouraged to implement a Post Cycle Therapy (PCT) plan after anabolic steroid use. Such a plan will commonly include the SERM’s Nolvadex and Clomid, and often additional HCG. This will greatly speed up the recovery process, as well as its overall efficiency. It will not return your natural testosterone levels to normal on its own, if this is something you’ve been told it is a myth. However, it will ensure you have enough testosterone for proper bodily function while your levels continue to naturally rise. Total recovery will still take several months, but this will cut the total time down dramatically and ensure a smooth recovery.