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Nolvadex (Tamoxifen) is one of the oldest and most popular selective estrogen receptor modulators (SERM’s) in the world. Tamoxifen Citrate was developed in 1961 by Imperial Chemical Industries (ICI) under the trade name Nolvadex. Later, AstraZeneca purchased ICI. Tamoxifen can be used to treat a large amount of dysfunctions, that’s why it was included in the World Health Organization’s list of essential medications. Nolvadex is also widely used by androgenic anabolic steroid users.
The drug was created to treat hormone-responsive breast cancer, then it turned out that it also can be used to prevent breast cancer. Nolvadex also can be used to treat women’s infertility, however studies have shown less effective results than from Clomid (Clomiphene).
In bodybuilding Tamoxifen can be used for two goals. The first option is as an anti-estrogen during an androgenic anabolic steroid cycle in order to prevent estrogen related side effects such as gynecomastia, bloating, high blood pressure, etc. However, similar to the case with Clomid (Clomiphene), I believe that there are more effective drugs such as Anastrozole or Proviron to prevent estrogenic side effects. The second most beneficial option is going through Post Cycle Therapy (PCT) in order to boost the Luteinizing Hormone and testosterone level.
Tamoxifen is a selective estrogen receptor modulator (SERM) with both estrogen agonist and antagonist properties. For the androgenic anabolic steroid users, one of the desired effects is in the prevention of gynecomastia. Tamoxifen also reduces other estrogenic side effects like water retention and blood pressure but not significantly. That’s why I recommend using other drugs to reduce the estradiol level like Anastrozole and Proviron, however Nolvadex can be used for a weak cycle and it has less side effects. Additionally, Nolvadex has a positive impact on cholesterol levels.
The most valuable effect of Nolvadex is boosting the testosterone level for Post Cycle Therapy (PCT). During the cycle your body stops producing its own testosterone because it realizes there are too many hormones. The rate of suppression depends on the steroid cycle, the more advanced the cycle the worse your natural testosterone level will be. Once the cycle is done the natural testosterone production will start slowly recovering again. However, after you’ve finished the cycle your natural testosterone level will be extremely low and it will take time to recover naturally.
No one, especially bodybuilders, would want to stay in a low testosterone condition because it can lead to high body fat, loss of muscles, etc.
Most athletes have a post cycle therapy plan in order to recover their testosterone level faster. Nolvadex one of the medications that is very effective in helping to recover the testosterone level. Nolvadex stimulates the higher release of both luteinizing hormone and follicle stimulating hormone. When the body indicates a rise in luteinizing hormone (LH) it starts producing testosterone. That helps in maintaining a higher testosterone level until your natural testosterone has completely recovered.
Dosages
In bodybuilding, for the purposes of post cycle therapy, your dosage should depend on the cycle. If the cycle was short (6-8 weeks) with one steroid or small steroids dosages you should use 20 milligrams for 14 days. If your cycle was advanced, the dosage of Nolvadex can be up to 50 milligrams per day for 6 weeks with gradually decreasing dosages. Also you can use a combination Nolvadex (Tamoxifen) with Clomid (Clomiphene) after advanced cycles.
The same as with Clomid it’s very important to start using Tamoxifen timely. After oral only cycles like Turinabol, Winstrol and Dianabol you should start using Nolvadex a day after your cycle is completed. If a cycle contains short duration esters, begin using Nolvadex 3 days after the cycle. If a cycle includes long lasting esters you should wait 14 days before using Nolvadex.
For the purpose of decreasing estrogenic side effects during an androgenic anabolic steroid cycle, the optimal dosage is from 10 to 20 milligrams per day. If this dosage does not help to protect from gynecomastia you should consider using aromatase inhibitors such as Anastrozole or Proviron.
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(Mesterolone)
Proviron represents one of the oldest anabolic androgenic steroids on the market. A product of the giant pharmaceutical company Schering, it would first appear in 1934. Officially known as Mesterolone, it has appeared under numerous brand names over the years, but the Proviron name has continually remained dominant. It has also remained one of the most misunderstood anabolic steroids among steroid users.
In many ways, Proviron is a very unique anabolic steroid. It shares some strong similarities to Masteron (Drostanolone) and to a degree Anavar (Oxandrolone) and Winstrol (Stanozolol) but in totality it is its own unique animal. In a performance capacity, Proviron is not used to promote large buildups in mass, although it can serve an important purpose during such a phase of training. We will, however, find Proviron to be far more common in cutting cycles, but once again its purpose will be somewhat unique.
As a therapeutic agent, Proviron is one of the most commonly used anabolic steroids in modern medicine. However, the Mesterolone hormone has never been approved by the U.S. FDA. It will primarily be found in European medicine, especially in Western Europe. The primary purpose of use is treating androgen deficiencies, age being the most common culprit of the condition. It is, however, also used in pre-pubescent males as well. The hormone is also used as a fertility aid in men and this alone makes it a very unique anabolic steroid as most anabolic steroids tend to have the opposite effect.
Mesterolone is a dihydrotestosterone (DHT) derived anabolic androgenic steroid. Specifically it is a structurally altered DHT hormone possessing the addition of a methyl group at the carbon one position. This allows the hormone to survive oral ingestion by protecting it from hepatic breakdown. This is one of the only oral anabolic steroids that is not C17-alpha alkylated (C17-aa) but instead carries the added methyl group. Oral Primobolan is the other most well-known oral steroid that carries this same methyl group. While the added methyl group does in fact protect it from breakdown, the total bioavailability of Proviron will be far less than most all C17-aa oral steroids. For this reason it has fallen out of popularity among many performance enhancing athletes but as we will see perhaps unjustifiably so.
Proviron carries an androgenic rating of 30-40 and an anabolic rating of 100-150. All ratings derive from and are measured against testosterone, which carries a rating of 100 in both categories. Despite having an anabolic rating that is potentially greater than testosterone, Proviron will display very low anabolic traits. This is very similar to Halotestin (Fluoxymesterone), which carries a massive anabolic rating but very little translatable anabolic activity. In the case of Proviron, while structurally very anabolic, the Mesterolone hormone converts and reduces to Diol metabolites, in turn reducing anabolic activity. However, Proviron’s androgenic rating is a different story. In fact, its translatable androgenic activity appears to commonly be higher than its structural rating would imply.
On a functional basis, Proviron carries four primary traits that largely define its mode of action. First and foremost the Mesterolone hormone has a strong binding affinity to Sex-Hormone-Binding-Globulin (SHBG). In fact, it appears to be one of the strongest anabolic steroids in this regard. By binding to SHBG, a hormone partially responsible for reducing free testosterone, binding SHBG will enhance the amount of circulating free testosterone. More importantly for the anabolic steroid user, it will make a larger percentage of the anabolic steroids used available in a free rather than bound state. A simple way to look at it is the anabolic steroids you’re taking become more powerful and potent.
Proviron also has the ability to interact with the aromatase enzyme, the enzyme responsible for the conversion of testosterone to estrogen. By binding to the aromatase enzyme, Proviron can actually inhibit aromatase activity, thereby offering protection against estrogenic side effects. It will not carry an anti-estrogenic effect near the level of power of an Aromatase Inhibitor (AI) but it will be notable. Depending on the nature of the cycle the individual undertakes it is quite possible for Proviron to take care of all your anti-estrogen needs.
The Mesterolone hormone will also carry a strong binding affinity to the androgen receptor. Once again this will promote the functionality of other steroids to a degree but more importantly promote enhanced metabolic activity through direct lipolysis. Then we’re left with the final issue that surrounds Proviron as a fertility medication. This is an anabolic steroid that does not suppress gonadotropins similarly to other anabolic steroids. With minimal suppression and its extremely strong androgenicity, this will enhance sperm production as androgens are necessary to spermatogenesis stimulation. This not only enhances the amount of sperm produced but greatly and equally important enhances the quality of the sperm. Before we go any further understand Proviron does have the ability to suppress gonadotropins, but there’s a line that has to be crossed for notable suppression to interfere with sperm production. This will make sense once we dive into the side effects section.
During a bulking phase Proviron is not going to be a foundational steroid, and for most men it will not have a place in an off-season cycle. There are exceptions and we’ll go over those here. Adding in Proviron could possibly help the individual breakthrough a sticking point during his cycle. At some point and time in all cycles the progress begins to wane, and in some cases come to a complete halt. By the way Proviron enhances the total free state of the other steroids being used in a stack, it could possibly help the individual breakthrough this sticking point. During the off-season, this is where most will use the largest amount of testosterone. Many will use large amounts during cutting cycles too, especially competitive bodybuilders but lower testosterone plans are more common during the cutting phase. However, there are those for numerous reasons who choose to run off-season cycles with limited testosterone doses. In such plans, including Proviron could give them a slight needed androgen boost. While it may not always be necessary it could prove to be beneficial.
Without question the best time to use Proviron will be during the cutting phase. This steroid has the ability to provide a bit of a hardening effect similar to Masteron, but more importantly the hardening effects of other steroids will be enhanced. Then we consider its strong binding to the androgen receptor, which will in fact enable the individual to burn body fat at a far more efficient rate. From here we must consider the anti-estrogen effect of Proviron. This will ensure the individual is less prone to water retention and as discussed, depending on the total cycle, it could negate the need for a traditional anti-estrogen. Then we’re once again left with the enhancement of circulating free testosterone. This can be a tremendous benefit when testosterone levels are often much lower during this phase of anabolic steroid use. In fact, with a low dosed testosterone cycle that includes other anabolic steroids, we can confidently say the total results will be greater for the individual who includes Proviron compared to the one who does not. In the end, the primary base benefit is the increased androgenicity of other steroids being used in order to promote a much harder and far more defined physique. It should be noted while Proviron can most certainly provide these traits they will not be noticeable unless you are lean.
There are possible side effects of Proviron use; however, this steroid carries one of the highest safety ratings among all anabolic steroids. Most men will be able to use this steroid without any negative issue, but possible side effects do exist despite a low probability. When it comes to female use, in a therapeutic or performance capacity this steroid cannot be recommended. The rate of virilization is much to high and should be avoided by females who wish to protect their femininity. In order to help you understand the possible side effects of Proviron, we have broken them down into their separate categories along with everything you need to know.
Anavar represents one of the most popular oral anabolic steroids of all time, and this is largely due to its well-tolerated nature. This is one of the few anabolic steroids that can be used safely by men and women, and it’s also one of the most side effect friendly. However, in some circles Anavar is greatly underappreciated due to its mild nature, but this is generally due to unrealistic expectations. Many tend to assume all anabolic steroids should yield a set of specific effects at a specific rate of power, but reality tells us varying steroids carry varying results and purposes. Anavar is without question an extremely beneficial anabolic steroid, but in order to appreciate its benefits we must understand it.
Anavar is the popular brand name associated with the dihydrotestosterone derived anabolic steroid Oxandrolone. The Oxandrolone hormone was first released in the early 1960’s under the trade name Anavar by G.D Searle & co. and was touted as carrying numerous therapeutic qualities. However, in 1989 Searle would discontinue the compound; this was largely due to FDA pressure that had tightened its grip on the anabolic steroid market. An important note; Searle also owned the licensing rights to the majority of Oxandrolone products on the global market, which would lead to this steroid nearly disappearing at this time. In 1995 the Oxandrolone hormone would reappear thanks to Bio-Technology General CORP (BTG), now Savient, under the trade name Oxandrin. BTG would hold a monopoly on the product during this time driving its cost through the roof. Thankfully, a few U.S. based pharmacies such as Watson would begin manufacturing generic Oxandrolone in recent years driving the cost down. However, it remains one of the more expensive anabolic steroids on the market, including when purchased from most underground labs. An important note for future purchase; while Anavar remains the common associated name for the Oxandrolone hormone, the Anavar name itself is not used by any human grade pharmaceutical company that manufactures Oxandrolone
Anavar or Oxandrolone is specifically a dihydrotestosterone (DHT) hormone that has been structurally altered. It is DHT with an added oxygen atom replacing the carbon-2 in the A-ring. This alteration greatly increases the hormone’s anabolic activity, as well as prevents it from being metabolically broken down. Anavar also possesses a second alteration at the 17th carbon position by the addition of a methyl group that allows the hormone to be ingested orally officially classifying Anavar as a C17-aa anabolic steroid.
As a therapeutic agent, Anavar has proven to be effective for numerous treatment plans. The most common reason the steroid is prescribed is for the purpose of weight gain necessitated due to surgery or infection or any type of severe weight loss. Anavar has also been proven to be extremely effective for treating over or prolonged exposure to corticosteroids, as well as for treating osteoporosis by the promotion of bone density. However, such uses are rare in the U.S. currently due to strict laws despite this steroid’s tremendously successful and positive track record. Anavar has also proven to be effective for treating hepatitis, as well as promoting growth and development in children who lack the necessary hormone production.
Anavar is also a very popular anabolic steroid among performance enhancing athletes. By looking at its therapeutic benefits, we should already have an understanding or appreciation as to what such benefits might be. While mild on its surface, Anavar carries a massive anabolic that is 3-6 times stronger than testosterone. Anavar’s anabolic rating is 322-630, while testosterone, a powerfully anabolic hormone carries a rating of 100. This would insinuate the muscle building properties of this steroid are tremendous; however, the rating does not translate into real life action quite like you might think. For the off-season male athlete, this will not be what we’d consider a premier bulking steroid; in fact, we’d call it weak for this purpose. But, its anabolic power will translate tremendously in a cutting cycle, or for the purpose of direct athletic enhancement. We will also find that the androgenicity of this hormone is rather low, making one of the friendliest steroids for female use.
When looking at the direct functions and traits of Anavar, the most important revolve around its ability to increase nitrogen retention in the muscle, decrease SHBG and inhibit glucocorticoid hormones. The increase in nitrogen retention will promote the anabolic atmosphere as reduced levels often lead to a catabolic state. The decrease in SHBG will yield a higher level of free testosterone in the body, not only providing more of an anabolic punch but promoting a free or unbound state of all circulating anabolic steroids. In simple terms, this makes the steroids being used more effective. As for the inhibition of glucocorticoid hormones, these are muscle wasting hormones; cortisol being the most well-known. Such hormones promote fat gain, as well as destroy lean muscle tissue. Anavar is also well-known for promoting increases in red blood cell count, which will enhance muscular endurance. Some studies have even shown this steroid has the ability to promote enhanced cardiovascular endurance. Last but not least, Anavar is one of the only true fat burning steroids. Most all anabolic steroids will enhance the metabolic rate, which will promote fat loss, but Anavar has been shown to directly promote lipolysis. Many attribute this to its ability to firmly bind to the androgen receptor, as well as in its ability to reduce thyroid-binding globulin, as well as increase thyroxine-binding prealbumin. This action results in the triiodothyronine hormone or T3 hormone being utilized to a higher degree. The fat burning results of Anavar are not entirely conclusive; there have been a few studies that produced alternate results as it pertains to fat loss. However, most data strongly supports the Oxandrolone hormone being a strong promoter of lipolysis.
Bulking/Off-Season: As the Oxandrolone hormone does not aromatize, any weight gained due to use will be lean muscle mass. Water retention is impossible due to the use of this steroid. However, massive gains often associated with steroid bulking cycles should not be expected with this steroid, it simply isn’t cut out for it. The individual should be able to gain some solid lean tissue and many report Anavar gains are easier to hold onto. But it won’t provide gains similar to well-known mass agents like Anadrol, Dianabol, Nandrolone or Testosterone. Some may find despite moderate gains that is all they want.
While Anavar is not the best off-season bulking steroid for men, when it comes to female use we must make an exception. Women are far more sensitive to Anavar than men, and it can be a very effective off-season agent. Further, most women are not looking for gains in size anywhere near male levels; often a slight increase in muscularity can be transforming.
Regardless of sex, all who use Anavar for off-season mass gaining phases will appreciate its metabolic enhancing traits. Those who supplement with the Oxandrolone hormone will find they gain less off-season body fat than they would have otherwise. Due to the increased levels of free testosterone, individuals will also find other steroids being used to be more potent. It may not be by a lot, but every last bit helps.
Fat Loss: Without question, male or female one of the best times to supplement with Anavar will be during the cutting phase. This will also be the most common purpose of use as the vast majority who use anabolic steroids participate in no competitive sports taking them out of the athletic enhancement category in an official sense. Due to its powerful anabolic nature, Anavar is one of the best steroids on earth for preserving lean tissue during the dieting phase. In order to lose body fat, we must burn more calories than we consume. The key to successful dieting is losing the desired fat while maintaining as much lean tissue as possible; however, muscle loss will occur. It does not matter how well-planned your diet is, some muscle loss will occur if a powerful anabolic agent is not present. Anavar is the agent you need due to the facts discussed above regarding its effects.
Those who supplement with Anavar during the cutting phase will also burn fat at a more efficient rate. Regardless of how powerful the direct lipolysis trait is or isn’t, the metabolic rate will still be greatly enhanced. Once lean, the individual will also find he appears harder and more defined. This is often accompanied by enhanced vascularity, and an overall tighter look.
Anavar is greatly appreciated by many athletes for a few specific reasons. This steroid will increase strength; the total increase will not be as significant as steroids like Dianabol and nowhere near the level of Halotestin, but it will be notable. Strength is one of the primary factors of successful athleticism as it translates into speed and power. Athletes also appreciate Anavar due to the fact that it won’t produce a large buildup in mass. In some cases, added mass might be a hindrance depending on the sport, and in other cases, it will bring about prying eyes that no athlete wants on them. When we further consider this steroid cannot lead to water retention, a possible burden to many athletes, Anavar rest as one of the top athletic choices.
Priority: Regardless of the purpose of use, all those who supplement with Anavar will find their rate of recovery is enhanced, as well as their muscular endurance. The individual will not tire out as fast, and he will be able to push longer and harder. This does not mean we should increase the duration of our training sessions, which may or may not be the case depending on the situation. However, we will make better use of each training session, we will make better use of our time on the field and all in all more quality work will be done.
Unlike another popular dihydrotestosterone derived anabolic steroid in Anadrol, Anavar is what we’d call a rather side effect friendly anabolic steroid. Side effects are certainly possible, but for the healthy adult they can be minimized. In fact, with responsible use, many will find they experience no negative effects at all. In order to understand the side effects of Anavar, we have broken them down into their separate categories with all the related information you’ll need.
The Oxandrolone hormone does not carry any estrogenic related side effects. It does not aromatize and cannot lead to gynecomastia or water retention due to increases in estrogen levels. It further carries no progestin related activity, which again supports no estrogenic related side effects. Due to water retention being impossible with this steroid, this will decrease the risk of high blood pressure. Excess water retention can promote high blood pressure. Some steroids that do not aromatize can lead to high blood pressure, such as Trenbolone, but Anavar is rarely associated with this trait.
Dianabol represents one of the most popular and one of the most important anabolic steroids of all time. Without question, this is the most popular oral steroid to ever hit the market and one of the most popular steroids in any form. While almost always found as an oral tablet, Dianabol can be found as an injectable solution, but the tablets represent the primary route of administration. Why is this steroid so important? In many ways it gave birth to the age of modern performance enhancement. It was not the first anabolic steroid used for that purpose, that would belong to testosterone, but Dianabol would open the door to a new wave of steroid use that has grown beyond what anyone expected.
Dianabol represents one of the only anabolic steroids that was developed for the sole purpose of performance enhancement. The compound did carry listed therapeutic uses at one time, but performance was the true reason this steroid was given life. Through the 1940’s and 50’s the Soviet Union had begun to dominate the Olympic games, and the use of testosterone by many of its athletes left the rest of the world lagging far behind. During this time, U.S. Olympic team Dr. John Ziegler would learn of the U.S.S.R.’s steroid use, and quickly would aid in ensuring his athletes would match up. In 1958, with the help of Dr. Ziegler, Ciba Pharmaceuticals would release the first batches of Methandrostenolone under the trade name Dianabol. The compound was designed in an effort to maintain the anabolic properties of testosterone with less androgenicity in a fast acting, powerful method. Seemingly overnight the steroid was a massive success, giving many U.S. athletes a distinct advantage over their Soviet rivals.
After its inception, Dianabol would quickly find its way into nearly every competitive sport imaginable. In conjunction with exogenous testosterone, this would birth an age of performance unlike the world had ever seen. The steroid would also rapidly become a staple in competitive bodybuilding where it has remained a favorite to this day. However, shortly after its release the U.S. FDA would begin to put a lot of pressure on Ciba in an effort to push the company to list true medical benefits of the steroid. The FDA would approve its use for the treatment osteoporosis in post-menopausal women as well as pituitary-deficient dwarfism, but the latter was withdrawn in the early 1980’s. Again the FDA would pressure Ciba for more information, but in 1983 under mounting pressure Ciba would discontinue the Dianabol tab. A few years later, the FDA would pull all Methandrostenolone brands from the shelf. Since that time Dianabol has not been legally manufactured in the United States, but is still manufactured heavily all over the world.
Methandrostenolone is a testosterone derived anabolic androgenic steroid. Officially, it is a structurally altered form of the primary male androgen testosterone. Dianabol is the testosterone hormone with an added double bond at the carbon one and two position. This slight alteration reduces the hormone’s androgenic nature. It also carries an added methyl group at the 17th carbon position that allows the hormone to survive oral ingestion, officially classifying Dianabol as a C17-alpha alkylated steroid. An important note, injectable Dianabol is also C17-alpha alkylated. The end result gives us an anabolic steroid with an androgenic rating of 40-60 with a much lower binding affinity to the androgen receptor compared to testosterone. However, it will also share a much weaker relationship for serum binding protein, which results in an extremely powerful anabolic steroid. If there’s any doubt, this is one extremely powerful anabolic steroid carrying a potent anabolic nature.
On a functional basis, Dianabol is one of the easier anabolic steroids to understand. This steroid will largely provide its anabolic benefits by enhancing protein synthesis, nitrogen retention and glycogenolysis. Protein synthesis represents the rate by which cells build proteins, the building blocks of muscle. Nitrogen retention, this is important as all muscle tissue is comprised of approximately 16% nitrogen. The more nitrogen we retain, the more anabolic we remain. Conversely, a nitrogen deficiency results in a catabolic or muscle wasting state. Then we’re left with glycogenolysis, which refers to the relationship and conversion between glycogen and glucose. Through enhanced glycogenolysis, we are able to make better use of our total carbohydrate consumption. While in many ways these traits are quite simple, they are strong enough to make Dianabol a remarkably powerful anabolic steroid.
Another important trait of Dianabol and perhaps one of the most important of all is the relationship it shares with other anabolic steroids. Dbol as it’s often called is not what we’d label as a base steroid. This is not an anabolic steroid we build a cycle around, but rather one we add to a well-planned stack. Dianabol has the ability to create unbelievable synergy when conjoined with other anabolic steroids. For example, you could supplement with 100mg of Trenbolone, Masteron or Equipoise per day (doses and steroids are simply being used as an example, not actual recommendations) and the results you’d receive from 50mg per day of Trenbolone, Masteron or Equipoise along side 50mg of Dianabol per day would be far more dramatic. You would have an identical amount of total milligrams of anabolic steroids with or without Dianabol, but the added Dianabol would provide greater enhancement.
The effects of Dianabol can be summed up as fast acting and dramatic. In fact, it is more than possible for the individual to gain as much as 20lbs of mass in only a few weeks of Dianabol use. Total dosing will play a role, as will total caloric consumption, but a 20lb gain is very realistic. This makes Dianabol a premier off-season bulking steroid, and that will be its most common purpose of use. During this phase of use, the individual should also expect his strength to increase significantly. Dbol is actually one of the best strength increasing steroids on the market and along with mass can produce this result rapidly.
The effects of Dianabol are also greatly appreciated by many athletes; however, it is not as common as it once was in athletic enhancement circles. Due to the possible rapid increases in mass, many athletes will opt for steroids like Anavar or Winstrol, but it generally depends on the purpose of use. Due to the rapid and pronounced increases in strength, which can translate into more power and speed, this can be a solid athletic enhancer. The individual should also experience a level of enhanced recovery and endurance. When it comes to the weight gain, it’s important to remember that this will largely revolve around total caloric intake. While the steroid can promote enormous amounts of mass, you have to feed the body enough calories to reach this end. We wouldn’t call this the best athletic enhancing steroid due to other options, but if strength is the only true concern it could be a decent option.
Then we’re left with the cutting cycle, and you will not find Dianabol in such plans too often. Some competitive bodybuilders will use it early on in a cutting phase in order to maintain fullness, and it will provide lean tissue protection; however, there are better options. One problem with cutting cycle use can be the level of water retention this steroid can provide, which is normally the last thing you want when cutting. Such retention can be controlled, and the ability for this steroid to maintain strength can be appreciated, but there are better options.
There are several possible side effects of Dianabol use. This is not the most dangerous anabolic steroid of all time, but it can carry a host of potential problems. A healthy adult male can manage the side effects of Dianabol, but you must understand them and how to combat them to pull this off. In order to achieve successful supplementation, we have broken down the possible side effects of Dianabol into their related categories along with all you need to know:
Dianabol is a relatively strong estrogenic anabolic steroid due to the moderate level of aromatase activity it carries. While its aromatase activity is only moderate, this conversion actually leads Methandrostenolone to be converted to methylestradiol rather than estradiol, which is far more powerful than estradiol. This can make side effects like gynecomastia and water retention very possible with this steroid; in fact, they can appear seemingly overnight. Heavy water retention can also promote high blood pressure, which Dianabol is notorious for causing. Such effects can be controlled, and when it comes to high blood pressure this is something you’ll need to put some effort into ensuring does not become a problem.
In order to combat the estrogenic side effects of Dianabol, anti-estrogens are commonly recommended when supplementing with this steroid. You have two choices in anti-estrogens, Selective Estrogen Receptor Modulators (SERM’s) like Nolvadex (Tamoxifen Citrate) and Aromatase Inhibitors (AI’s) like Femara (Letrozole). SERM’s can be enough for some men and should be your first choice if they can get the job done. However, AI’s will be far more effective as they will directly inhibit aromatization and reduce serum estrogen levels. Unfortunately, AI’s can negatively affect cholesterol, as can Dianabol, and when conjoined this can prove potentially problematic. If an AI is used cholesterol management will be a priority, and it will be possible. However, SERM’s, while not always as effective will actually promote healthier cholesterol levels due to their estrogenic like activity in the liver.
Dianabol is not an extremely androgenic steroid, its androgenicity has been structurally reduced, but androgenic side effects are still possible. Such side effects of Dianabol use include acne, accelerated hair loss in those predisposed to male pattern baldness and body hair growth. Most men should not have a problem with such effects, response will be the final dictator, but most will remain clear. Although the odds are in your favor, such effects are brought on by Methandrostenolone being metabolized by the 5-alpha reductase enzyme. This is the same enzyme responsible for the reduction of testosterone to dihydrotestosterone, but the overall conversion here will result in very low amounts of dihydromethandrostenolone. This tells us 5-alpha reductase inhibitors like Finasteride that are often used to combat androgenic side effects will have very little if any affect on Dianabol.
Despite its reduced androgenicity, Dianabol can promote virilization symptoms in women. Such symptoms include body hair growth, a deepening of the vocal chords and clitoral enlargement. It is possible for some women to use this steroid without virilization symptoms with extremely low doses, but the odds are not favorable. Most all women should choose anabolic steroids with less translating androgenic activity to meet their needs.
Dianabol can have a pronounced negative effect on cholesterol. This includes HDL cholesterol suppression and increases in LDL cholesterol, and the total changes can be significant. It is possible for total cholesterol levels to remain in a healthy range, but it is also possible for this healthy total reading to be misleading if HDL is suppressed heavily. Managing cholesterol during Dianabol use will be extremely important. Repeated use of this steroid as with many anabolic steroids could potentially lead to plaque buildup in the arteries overtime. It’s also extremely important to keep in mind the very possible additional strain on cholesterol brought on by the use of an AI when supplementing with Dianabol as total estrogen reductions will have a negative effect. Again, cholesterol maintenance will be extremely important.
As discussed, Dianabol can also play a negative role on blood pressure, which can be controlled by controlling water retention in most cases. When it comes to the blood pressure and cholesterol issues, the ultimate key to success will be your lifestyle. You should not supplement with this steroid if you already suffer from high blood pressure or cholesterol. If you are healthy enough for use, you should ensure your lifestyle is conducive to their maintenance. This should include a healthy diet that is rich in omega fatty acids, plenty of cardiovascular activity and an avoidance of any activity that promotes the opposite, negative end. Proper estrogen maintenance and control will also be important as estrogen plays an important role in cholesterol management. Yes, it is more than possible to supplement with Dianabol without high blood pressure and cholesterol, but you must put in the effort.
All anabolic steroids suppress natural testosterone production. While the total rate of suppression varies from one steroid to the next, with Dianabol it is very pronounced. For this reason, most men are encouraged to include some form of exogenous testosterone with their Dianabol use. Failure to include exogenous testosterone, regardless of your genetics or rumors you have heard will lead to a low testosterone condition. Such a condition comes with a host of possible symptoms and is extremely unhealthy. Even if symptoms do not show or are moderate at best, a low level condition will remain an unhealthy one. If you include exogenous testosterone, this problem is solved as the body will have all the testosterone it needs.
Once the use of Dianabol is complete and all the exogenous steroidal hormones have cleared your system, natural testosterone recovery will begin again. Natural recovery assumes no prior low testosterone condition. It also assumes no damage was done to the Hypothalamic-Pituitary-Testicular-Axis (HPTA) due to improper anabolic steroid use. While natural recovery will begin on its own, it will be slow. For this reason, most are encouraged to implement a Post Cycle Therapy (PCT) plan after anabolic steroid use. Such a plan will commonly include the SERM’s Nolvadex and Clomid, and often additional HCG. This will greatly speed up the recovery process, as well as its overall efficiency. It will not return your natural testosterone levels to normal on its own, if this is something you’ve been told it is a myth. However, it will ensure you have enough testosterone for proper bodily function while your levels continue to naturally rise. Total recovery will still take several months, but this will cut the total time down dramatically and ensure a smooth recovery.
Winstrol is one of the most popular and well-known anabolic steroids on earth. Developed by Winthrop Laboratories in the late 1950’s, this is an anabolic steroid that has gotten a lot of media attention over the years. In fact, those who have never used anabolic steroids, if they can name a steroid it’s usually Winstrol or Stanozolol. The name Winstrol is actually the most commonly associated brand name of the Stanozolol hormone. This is an anabolic steroid that has garnered worldwide attention due to numerous athletic scandals over the years. When various athletes have been caught using anabolic steroids, Winstrol has been at the forefront of the scandal countless times. In fact, it is associated with the most important athletic steroid scandal in history.
In 1988, Canadian sprinter Ben Johnson tested positive for the steroid after taking the gold at that year’s Summer Olympics. Not only did Johnson destroy his competition, he handedly defeated the highly favored Carl Lewis with relative ease. This would lead to Stanozolol making countless news headlines for a very long time and more importantly truly usher in the U.S. government’s war on steroids. The Johnson scenario is not the largest athletic based steroid scandal to ever occur, which would probably belong to the decades long East German doping machine; however, the Johnson scandal would have the largest impact. When Ben Johnson destroyed the U.S. golden boy, many point to this as being the final nail in the coffin that the U.S. congress needed to justify classifying anabolic steroids as Schedule III controlled substances.
While one of the more well-known anabolic steroids, Winstrol is very popular among most in the steroid using population. It is in many ways a fairly mild anabolic steroid that can be safely used by men and women. Equally important, it has proven highly effective for numerous performance enhancement endeavors. It is a long standing favorite among competitive bodybuilders and physique based athletes during cutting or contest prep phases. It is also a top steroid of choice for numerous performance athletes due to its ability to promote strength and endurance without unwanted mass.
Beyond performance enhancement, Winstrol has had a lot of success in modern medicine. It has been successfully used to combat lean tissue wasting and has had a lot of success in preserving bone mass in cases of osteoporosis. Winstrol has also been used to combat prolonged exposure to corticosteroid treatment, given to burn victims and even used to aid in the healing of severe bone fractures. The steroid has also enjoyed a little success in treating obesity when hormonal assistance is needed, as well as treating delayed growth in some children. As the years have passed, Winstrol has remained available for treatment for most of these conditions as well as being proven highly successful in treating angioedema among a few other treatment plans such as specific forms of breast cancer. The steroid has never lost FDA approval and unlike many anabolic steroids has maintained approval for numerous therapeutic treatment plans.
Stanozolol is a dihydrotestosterone (DHT) derived anabolic androgenic steroid, or more specifically a structurally altered form. Stanozolol is the DHT hormone with two structural changes that give us the Winstrol compound. The first alteration is the introduction of an attached pyrazol group at the A-ring of the hormone replacing the 3-keto group. This modification officially classifies Stanozolol as a heterocyclic steroid. The hormone also carries an added methyl group in order to protect hormone after administration. This structural change takes place at the 17th carbon position officially classifying Stanozolol as a C17-alpha alkylated (C17-aa) anabolic steroid.
Due the combination of structural changes, this reduces the hormone’s androgenicity significantly and greatly increases its anabolic power. Officially Winstrol carries an anabolic rating of 320 and an androgenic rating of 20. More importantly, its ratings translate perfectly in real life effects giving us an extremely beneficial anabolic steroid.
Winstrol carries many positive steroidal traits, one of which is its ability to lower Sex-Hormone-Binding-Globulin (SHBG) significantly. This allows for more of the steroids being supplied to rest in an unbound state, as well as provides an increase in free testosterone. While many anabolic steroids lower SHBG Winstrol appears to have a much stronger affinity than most. In fact, studies have demonstrated nearly 50% reductions in SHBG in mere days of use and even at relatively low doses.
Beyond a reduction in SHBG, which is one of its primary traits, Winstrol will enhance protein synthesis and greatly increase nitrogen retention in the muscles. The steroid will also do a fairly decent job at increasing red blood cell count and inhibiting glucocorticoid hormones but not to the degree of many other steroids. In many ways, we have a mild yet evenly possession of some basic steroidal traits coupled with the dramatic SHBG reduction that gives us a controllable and unique compound. This really is one of the easiest anabolic steroids to understand.
When looking at the direct functions and traits of Winstrol there is one more issue we need to discuss. The Stanozolol hormone is both an injectable an oral anabolic steroid. Both forms are comprised of the same identical Stanozolol hormone. 1mg of one form is the same as 1mg of the other form. Some studies have suggested oral Winstrol may reduce SHBG a little more than its injectable counterpart, while others have said injectable forms may be slightly more potent on an overall milligram for milligram basis. However, overall these appear to be rather insignificant differences regardless of the direction they go. In fact, the individual should be able to receive the same identical benefits with either form.
Another important note often misunderstood about Winstrol forms is the C17-aa nature. Both oral and injectable Stanozolol are C17-aa anabolic steroids. Most oral steroids are C17-aa and while injectable steroids rarely are injectable Stanozolol is one of the exceptions. The injectable form is also commonly referred to as Winstrol Depot.
Although used to stave off lean tissue wasting, Winstrol is not what we’d call a bulking steroid. You will rarely find this steroid in an off-season mass gaining stack. However, it could be used in an effort to enhance the activity of the other steroids being used due to the strong SHBG reduction it will provide but this is generally not recommended. When we dive into the side effects of Winstrol, we will find it is very hepatotoxic and use should be limited to when it’s most valuable. For the male athlete, this will not be during the bulking phase.
When it comes to off-season bulking, we could make more of an exception with female use. Females are far more sensitive to the steroid and short burst plans could be very beneficial during this phase. But again, there are probably better options.
The effects of Winstrol are undoubtedly most beneficial to direct performance enhancement of an athletic nature. We’re talking about functional competitive athletes, not bodybuilders or physique athletes. This steroid has the ability to greatly increase strength and this can translate into both power and speed. Further, it will accomplish this without adding a lot of additional weight that could hinder some depending on the sport, as well as cause unwanted attention from prying eyes. There have been those who have said Winstrol isn’t good for competitive athletes, especially those athletes in explosive sports due to potential weakening of the tendons but this is more or less message board anecdotal hysteria that supports this claim. In fact, many studies have shown it can have a positive impact on strengthening tendons and we already know it’s good for the bones. If not, it wouldn’t be used to treat osteoporosis.
There are also some who complain of joint pain when using Winstrol. As a steroid that does not aromatize there will be no water retention but the “dry feeling” may not be what many think it is. Most who use the steroid will be physique athletes or gym rats during a cutting phase. They will also typically add it into a plan late in the diet once they’re already lean. Typically, when you become very lean, bodybuilding lean, this makes the joints a little uncomfortable. With or without Winstrol this discomfort could potentially exist. As for pro athletes who have nearly every last steroid at their disposal, remember, if Winstrol weren’t effective in competitive sports so many athletes wouldn’t make it a primary and favorite choice. In fact, the combo of Winstrol with low doses of Nandrolone is a very common stack among many athletes, and this stack will greatly eliminate any potential joint discomfort should it exist.
Beyond athletics, the gym rat or bodybuilding effects of Winstrol will be best displayed once you’re already somewhat lean. The steroid will help produce a dryer, harder look but only if you’re relatively lean. It will also aid in lean tissue preservation but not to a very strong degree that’s often needed in such a phase. It’s typically recommended that Winstrol only be used in this capacity as a secondary steroid, not a base or foundational steroid.
Both men and women can greatly benefit from Winstrol during the cutting phase. While it won’t be the best lean tissue preserver, many report maintaining more of their strength that is often lost when dieting when Winstrol is in play. Vascularity should also become more pronounced and overall the individual should enjoy an overall enhancement in definition.
The side effects of Winstrol most certainly exist, but they largely fall into the category of possible rather than guaranteed. The side effects of Winstrol can be controlled but it will take some effort on your part. There is also always the issue of individual response. We all respond to different things differently. This not only holds true with various anabolic steroids but all things we put into our body. Most of use can take Aspirin, but there are others who will experience horrible side effects if they touch the first pill. Most of us can tolerate dairy products, but there are others who become very sick if they even look at a glass of milk. Individual response dictates quite a lot. With that in mind, in order to help you understand the possible side effects of Winstrol we have broken them down into their separate categories along with all you’ll need to know.